Protein Alignment Mec2 and Phb1

DIOPT Version :10

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: XP_309992.2
• Gene: Phb1 / 1271235
• VectorBaseID: AGAMI1_014007
• Length: 272
• Species: Anopheles gambiae
• Alignment Length: 225
• Identity: 59/225 - (26%)
• Similarity: 103/225 - (45%)
• Gaps: 38/225 - (16%)

  Fly    97 RAIIFRLGRLSG---GARGPGMFFILPCIDEYRKVDLRTVTFNVPQQEMLT--KDSVTVTVDAVV 156
            ||:||  .|.||   ...|.|..|.:|.:......|:|:...|||   ::|  ||...|.:...:
Mosquito    35 RAVIF--DRFSGVKQQVTGEGTHFFVPWVQRPIIFDIRSQPRNVP---VITGSKDLQNVNITLRI 94

  Fly   157 YYR-ISDPLYAVIQVEDYSMSTRLLAATT---LRNIVGTRNLSELLTERETLAHNMQATLDEATE 217
            .:| :.|.|..:..:.......|:|.:.|   |:.:|...:..||:|:||.::..:...|.|...
Mosquito    95 LFRPVPDQLPKIYTILGQDYDERVLPSITTEVLKAVVAQFDAGELITQREMVSQKVSDDLTERAA 159

  Fly   218 PWGVMVERVEI------KDVSLPVSMQRAMAAEAEAAR--------DARAKVIAAEGEKKS---- 264
            .:||:::.:.|      |:.:..|.|::....|||.||        ..:|.:|.|||:.::
Mosquito   160 QFGVILDDISITHLTFGKEFTQAVEMKQVAQQEAEKARFMVEKAEQMKQAAIITAEGDAQAAQML 224

  Fly   265 ATALKEASDVISASPSALQLRYLQTLSSIS 294
            |.:|||:.|      ..::||.::....|:
Mosquito   225 ARSLKESGD------GLIELRRIEAAEDIA 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	SPFH_like	107..314	CDD:473137	54/215 (25%)
Phb1	XP_309992.2	SPFH_prohibitin	27..221	CDD:259799	51/190 (27%)