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Protein Alignment Mec2 and PHB2

DIOPT Version :10

Sequence 1:	NP_573357.1	Gene:	Mec2 / 32905	FlyBaseID:	FBgn0030993	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001138303.1	Gene:	PHB2 / 11331	HGNCID:	30306	Length:	299	Species:	Homo sapiens

Alignment Length:	293	Identity:	65/293 - (22%)
Similarity:	117/293 - (39%)	Gaps:	102/293 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 RAIIFRLGRLSGGAR----GPGMFFILPCIDEY----------RKV-------DLRTVTFNV--- 137
            |||.|  .|:.|..:    ..|:.|.:|.. :|          ||:       ||:.|..::
Human    48 RAIFF--NRIGGVQQDTILAEGLHFRIPWF-QYPIIYDIRARPRKISSPTGSKDLQMVNISLRVL 109

  Fly   138 --PQQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVEDYSMSTRLLAA---TTLRNIVGTRNLSEL 197
              |..:.|..          :|.|:.         .||  ..|:|.:   ..|:::|...|.|:|
Human   110 SRPNAQELPS----------MYQRLG---------LDY--EERVLPSIVNEVLKSVVAKFNASQL 153

  Fly   198 LTERETLAHNMQATLDEATEPWGVMVERVEIKDVSL-----------PVSMQRAMAAE---AEAA 248
            :|:|..::..::..|.|..:.:.::::.|.|.::|.           .|:.|.|..|:   .:|.
Human   154 ITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAK 218

  Fly   249 RDARAKVIAAEGEKKSATALKEASDVISASPSALQLRYLQTLSSIS---AEKNSTIIFPLPMELL 310
            ::.|.|::.||||.::|..|.||   :|.:|..::||.::...:||   |...:.|
Human   219 QEQRQKIVQAEGEAEAAKMLGEA---LSKNPGYIKLRKIRAAQNISKTIATSQNRI--------- 271

  Fly   311 TPYLAKYAHLMGPPPELKQSPEKSDNIVLDALD 343
              ||.                  :||:||:..|
Human   272 --YLT------------------ADNLVLNLQD 284

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.