Protein Alignment Mec2 and nphs2

DIOPT Version :9

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: XP_017949096.1
• Gene: nphs2 / 100498000
• XenbaseID: XB-GENE-485101
• Length: 376
• Species: Xenopus tropicalis
• Alignment Length: 295
• Identity: 131/295 - (44%)
• Similarity: 188/295 - (63%)
• Gaps: 16/295 - (5%)

  Fly    47 TTQQYRGFKTSENEPKG--CMEWVVTLFSVLIFIITSPIAIFICFKVVAEYERAIIFRLGR-LSG 108
            |:|:..|.|     |.|  ..|.::....:|:.|:|.|::|:.|.|||.|||||:|||||| |||
 Frog    80 TSQKDDGVK-----PAGFRVFEGLLIFCCLLLVILTLPLSIWFCVKVVREYERAVIFRLGRMLSG 139

  Fly   109 GARGPGMFFILPCIDEYRKVDLRTVTFNVPQQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVEDY 173
            .|||||:||.|||:|:..|||.|..||.||..:::|||.||:.:|.:.|||:.:....:..|...
 Frog   140 RARGPGLFFYLPCLDKCHKVDFRLKTFEVPFHQIVTKDLVTLEIDVICYYRLENACLFLTSVSSI 204

  Fly   174 SMSTRLLAATTLRNIVGTRNLSELLTERETLAHNMQATLDEATEPWGVMVERVEIKDVSLPVSMQ 238
            |.:.:||..||.:.::..|...::|.||:::...::..||.||..||:.|||.|||||.||..::
 Frog   205 SSAFQLLVQTTTKRLLAHRAFLDILLERKSIGEEVKVALDAATCHWGIKVERTEIKDVKLPEEVK 269

  Fly   239 RAMAAEAEAARDARAKVIAAEGEKKSATALKEASDVISASPSALQLRYLQTLSSISAEKNSTIIF 303
            ::||.||||.|.|:.|||||||||..:..:|.|::.:|.||:|:|||||.||..:::||.:|.:.
 Frog   270 QSMAVEAEAQRHAKVKVIAAEGEKTVSEYIKLAAEKLSGSPTAIQLRYLHTLQCMTSEKPATFVL 334

  Fly   304 PLPMELLTPYLAKYAHLMGPPPELKQSPE--KSDN 336
            |||.:|:.  |...|.|    ||:..:|.  ||||
 Frog   335 PLPFDLMN--LNAVARL----PEINPTPNTPKSDN 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	PHB	88..238	CDD:214581	72/150 (48%)
		SPFH_like	107..314	CDD:302763	93/206 (45%)
nphs2	XP_017949096.1	SPFH_podocin	116..338	CDD:259809	107/221 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062075at2759
OrthoFinder	1	1.000	-	-		FOG0000760
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010