DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7556 and ERJ5

DIOPT Version :9

Sequence 1:	NP_001285427.1	Gene:	CG7556 / 32902	FlyBaseID:	FBgn0030990	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_116699.3	Gene:	ERJ5 / 850602	SGDID:	S000001937	Length:	295	Species:	Saccharomyces cerevisiae

Alignment Length:	286	Identity:	71/286 - (24%)
Similarity:	125/286 - (43%)	Gaps:	66/286 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RPELTLAGLLLLCATGASAWHSEELEIFDLVEEV------NRNFYEFMGIN--QTATGAEVKRAF 60
            :|.|.:.||:.|    :.|:.:.|.|||.|..|:      :.|||:|:.:.  |.::..|:.:..
Yeast     6 KPALVVLGLVSL----SYAFTTIETEIFQLQNEISTKYGPDMNFYKFLKLPKLQNSSTKEITKNL 66

  Fly    61 RTLSIVLHPDKNPAEDANIQFRNLVSIYEVLKDPSRREKYDRVLKEGMPNW--KSALYYYRRMRK 123
            |.||...||||||......:..||.:  ::|.:.|.|:.||..|:.|.||:  ....:|:.||:.
Yeast    67 RKLSKKYHPDKNPKYRKLYERLNLAT--QILSNSSNRKIYDYYLQNGFPNYDFHKGGFYFSRMKP 129

  Fly   124 IGLYEGAFILFLITTVGQYLFAWAAYLEKKYTAEQVF----------GTKLKKLQKKNKNID--- 175
            ...:..||| :::..:|||:.:...|..::...|...          |..:|:|..|....|
Yeast   130 KTWFLLAFI-WIVVNIGQYIISIIQYRSQRSRIENFISQCKQQDDTNGLGVKQLTFKQHEKDEGK 193

  Fly   176 ------MDVILSE------------IPMPSLLNTLPIQIPLALWNL------------------P 204
                  .||.:.|            :..||:.|.|..:||.::||:                  .
Yeast   194 SLVVRFSDVYVVEPDGSETLISPDTLDKPSVKNCLFWRIPASVWNMTFGKSVGSAGKEEIITDSK 258

  Fly   205 RTIKNGFSKANELKELALEKRRQELE 230
            :...|...|.|::|:.:.:|.::::|
Yeast   259 KYDGNQTKKGNKVKKGSAKKGQKKME 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7556	NP_001285427.1	DnaJ	40..101	CDD:278647	20/62 (32%)
		SANT	301..>341	CDD:197842
		SANT	304..341	CDD:238096
		SANT	399..447	CDD:197842
		SANT	400..447	CDD:238096
ERJ5	NP_116699.3	CbpA	41..271	CDD:225124	56/232 (24%)
ERJ5	NP_116699.3	DnaJ	44..105	CDD:395170	20/62 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005801
OrthoInspector	1	1.000	-	-		oto99203
orthoMCL	1	0.900	-	-		OOG6_105968
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1934
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740