Protein Alignment CG7556 and DNAJC1

DIOPT Version :9

• Sequence 1: NP_001285427.1
• Gene: CG7556 / 32902
• FlyBaseID: FBgn0030990
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_071760.2
• Gene: DNAJC1 / 64215
• HGNCID: 20090
• Length: 554
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 180/569 - (31%)
• Similarity: 269/569 - (47%)
• Gaps: 160/569 - (28%)

  Fly     5 PELTLAGLLLLCATGASAWHSEELEIFDLVEEVNRNFYEFMGINQTATGAEVKRAFRTLSIVLHP 69
            |.|.|..|||.....|..|.|.:||:|||||||..|||:|:|:.|.|:.|::::|:|.||:.|||
Human    30 PLLWLLLLLLAAVAPARGWESGDLELFDLVEEVQLNFYQFLGVQQDASSADIRKAYRKLSLTLHP 94

  Fly    70 DKNPAEDANIQFRNLVSIYEVLKDPSRREKYDRVLKEGMPNWKSALYYYRRMRKIGLYEGAFILF 134
            |||..|:|..|||.||:|||||||..||::||.:|..|:|:|:..::||||:||:...|.|.:||
Human    95 DKNKDENAETQFRQLVAIYEVLKDDERRQRYDDILINGLPDWRQPVFYYRRVRKMSNAELALLLF 159

  Fly   135 LITTVGQYLFAWAAYLEKKYTAEQVFGTKLKKLQKK--NKNIDMDVI-LSE-----IPMPSLLNT 191
            :|.|||.|...|:.||||:  .:::...|.::.:||  :|::|:..: .||     :..|...:.
Human   160 IILTVGHYAVVWSIYLEKQ--LDELLSRKKREKKKKTGSKSVDVSKLGASEKNERLLMKPQWHDL 222

  Fly   192 LPIQIPLALW------NLPRTIKNGFSKANELKELALEKR-----RQELEAVRRQEELER----- 240
            ||.:  |.:|      .||..|::......:.||..|:::     |.|||.:::|:::::
Human   223 LPCK--LGIWFCLTLKALPHLIQDAGQFYAKYKETRLKEKEDALTRTELETLQKQKKVKKPKPEF 285

  Fly   241 ---------------------EAEEQARLRKEHKENLRKRKQNSKAPEKTEEELRGYSQIQTREL 284
                                 |.|||   ..:..|| |.|.|..:|||
Human   286 PVYTPLETTYIQSYDHGTSIEEIEEQ---MDDWLEN-RNRTQKKQAPE----------------- 329

  Fly   285 TDDDAVRPASQKSTVSGGFWTDEDLTELIRLVKKYPGGAGSRWNTIAESMNRSVQEVTFMAAKMK 349
                               ||:|||::|.|.:.|:|||...||..||..:.|||.:||..|.::|
Human   330 -------------------WTEEDLSQLTRSMVKFPGGTPGRWEKIAHELGRSVTDVTTKAKQLK 375

  Fly   350 ENGYRIPGQT-----------------------DSV-----AEALVQESQQ-------------- 372
            ::....||..                       |.:     ||.:..|.:|
Human   376 DSVTCSPGMVRLSELKSTVQNSRPIKTATTLPDDMITQREDAEGVAAEEEQEGDSGEQETGATDA 440

  Fly   373 -AQRKEKVKKAAANA--------GASAEKSMLIPETN-------------------WTQEQQRAL 409
             .:|::..:...|.|        .|..:|...|.|.|                   |||.||:.|
Human   441 RPRRRKPARLLEATAKPEPEEKSRAKRQKDFDIAEQNESSDEESLRKERARSAEEPWTQNQQKLL 505

  Fly   410 EAAIVKYRKTAGGDRWQKIANSVPEKTKEECLVRYKYLCELVKTQKRAE 458
            |.|:.:|.: ...|||.|||..||.|:||:|:.|||.|.|||:.:|:|:
Human   506 ELALQQYPR-GSSDRWDKIARCVPSKSKEDCIARYKLLVELVQKKKQAK 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7556	NP_001285427.1	DnaJ	40..101	CDD:278647	34/60 (57%)
		SANT	301..>341	CDD:197842	18/39 (46%)
		SANT	304..341	CDD:238096	18/36 (50%)
		SANT	399..447	CDD:197842	25/66 (38%)
		SANT	400..447	CDD:238096	25/65 (38%)
DNAJC1	NP_071760.2	DnaJ	65..126	CDD:278647	34/60 (57%)
		SANT	329..375	CDD:238096	22/81 (27%)
		SANT	495..544	CDD:197842	25/49 (51%)
		SANT	496..543	CDD:238096	24/47 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145112
Domainoid	1	1.000	85	1.000	Domainoid score	I8207
eggNOG	1	0.900	-	-		E1_KOG0724
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I3391
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46576
OrthoDB	1	1.010	-	-		D412930at33208
OrthoFinder	1	1.000	-	-		FOG0005801
OrthoInspector	1	1.000	-	-		oto88960
orthoMCL	1	0.900	-	-		OOG6_105968
Panther	1	1.100	-	-	LDO	PTHR44653
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1934
SonicParanoid	1	1.000	-	-		X5521
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800