DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7556 and dnj-11

DIOPT Version :9

Sequence 1:	NP_001285427.1	Gene:	CG7556 / 32902	FlyBaseID:	FBgn0030990	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_501006.1	Gene:	dnj-11 / 177419	WormBaseID:	WBGene00001029	Length:	589	Species:	Caenorhabditis elegans

Alignment Length:	524	Identity:	117/524 - (22%)
Similarity:	218/524 - (41%)	Gaps:	136/524 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NRNFYEFMGINQ---TATGAEVKRAFRTLSIVLHPDKNPAEDANIQ----FRNLVSIYE-VLKDP 94
            |::.|:.:|:::   .||..|::..:|...:..||||.......::    |..:...|| |....
Worm    96 NQDHYKVLGLSKLRWQATSDEIRFCYRQKVLKHHPDKKKHRGIVMEKEEYFTCITKAYEQVGMSD 160

  Fly    95 SRREKYDRV---LKEGMPNWKSALY--YYRRMRKIGLYEGAFI-LFLITTVGQ-----------Y 142
            .:|:.:|.|   ..:.:||.||..:  :|..:..:......:. :..:..:|:           |
Worm   161 VKRQAFDSVDHKFNDIIPNEKSINHNNFYNELAPVFQLNSRWSNIKPVPELGKSDATREDVENFY 225

  Fly   143 LF-----AWA--AYL--EKKYTAEQVFGTKLKKLQKKNKNIDMDVILSEIPMPSLLNTLPIQIPL 198
            .|     :|.  :||  |.|...|..:  :.::::|:||      ...|.........:...:.:
Worm   226 DFWFNFQSWREFSYLDEEDKERGEDRY--ERREMEKQNK------AERERRRKEEAKRIRKLVDI 282

  Fly   199 ALWNLPRTIKNGF--------SKANELKELAL---------EKRRQELEAVRRQEELEREAEEQA 246
            |....||.||  |        .||.|.|:.|:         |||.:|....:::||.:|:|:|:.
Worm   283 AYAKDPRIIK--FKKEQQAKKDKAKEDKQRAIREKQEAIDREKREKEEAEAKQKEEADRKAKEER 345

  Fly   247 RLRKEHKENLRK-----RKQNSKAPEK-------------------------TEEELRGY----- 276
            ...|:.::..:|     ||:..|..::                         |.::||..
Worm   346 EREKKERDIAKKAMSQQRKRLKKLADEAGHWTENPRDKLTEMERIERICIGFTVDQLRELCEKVE 410

  Fly   277 -----SQIQTRELTDDDAVR--PASQKSTVSGG------------FWTDEDLTELIRLVKKYPGG 322
                 |:||| .|||.:.::  .|..|.|::..            .||.|::..|::....:|.|
Worm   411 SLSIASEIQT-ALTDAEILKKEAAGAKVTITEDKNKENEKQADKETWTSEEIQLLVKASNTFPPG 474

  Fly   323 AGSRWNTIAESMNRSVQEVTFMAAKMKENGYRIPGQTDSVAEALVQESQQAQRKE-KVKKAAANA 386
            ...||..||:.:|...::.|           .:|.:|:   :.::::.:..|... |:.....|.
Worm   475 TVERWVQIADYINEHRKDST-----------GLPPKTE---KQVIKQCKAVQTMNVKLPSTTQNQ 525

  Fly   387 GASAEKSMLIPETNWTQEQQRALEAAIVKYRKTAGGDRWQKIANSVPEKTKEECLVRYKYLCELV 451
            ..:|    |..|..|:..:|:.||.||.|: |::..:||:||:..|..|:|:.|:.|:|||.::|
Worm   526 LGTA----LPDEDVWSATEQKTLEDAIKKH-KSSDPERWEKISTEVGTKSKKACIRRFKYLVQMV 585

  Fly   452 KTQK 455
            |.:|
Worm   586 KNKK 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7556	NP_001285427.1	DnaJ	40..101	CDD:278647	15/68 (22%)
		SANT	301..>341	CDD:197842	11/51 (22%)
		SANT	304..341	CDD:238096	11/36 (31%)
		SANT	399..447	CDD:197842	18/47 (38%)
		SANT	400..447	CDD:238096	18/46 (39%)
dnj-11	NP_501006.1	ZUO1	61..441	CDD:227594	74/355 (21%)
		DnaJ	98..167	CDD:278647	15/68 (22%)
		SANT	455..509	CDD:238096	14/67 (21%)
		SANT	536..584	CDD:197842	20/48 (42%)
		SANT	536..582	CDD:238096	19/46 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810