DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Inx5 and Inx3

DIOPT Version :9

Sequence 1:	NP_573353.2	Gene:	Inx5 / 32901	FlyBaseID:	FBgn0030989	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001263050.1	Gene:	Inx3 / 44266	FlyBaseID:	FBgn0265274	Length:	395	Species:	Drosophila melanogaster

Alignment Length:	427	Identity:	136/427 - (31%)
Similarity:	211/427 - (49%)	Gaps:	71/427 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFSAVKPLSK--YLQFKSIRIYDSVFTIHSRCTVVILLTCSLLLSARQYFGDPIQCISEEK-NIE 62
            |.|||....|  ||..|:: |.:.||..|.|.|..||.||.::::|....||||.||::.. .:.
  Fly     6 MVSAVSGFIKIRYLLDKAV-IDNMVFRCHYRITTAILFTCCIIVTANNLIGDPISCINDGAIPMH 69

  Fly    63 YIQSYCWTMGTYILKLDDFGDQEQALVSPNQEVSYNSAFFSSATTNAPQSSSRVRTRPHFRSSLR 127
            .|.::||...||.:              |.|:                          |     |
  Fly    70 VINTFCWITYTYTI--------------PGQQ--------------------------H-----R 89

  Fly   128 RIGEYNEAYARSLSIA-EGVGPEIRGQTERQYLRYYQWVIILLLFQSFVFYFPSCLWKVWEGRRL 191
            :||         ..:| .|:|.|. || |::|..|||||..:|.||..:||.|..:||..|..::
  Fly    90 QIG---------TDVAGPGLGNEY-GQ-EKRYHSYYQWVPFVLFFQGLMFYVPHWVWKNMEDGKI 143

  Fly   192 KQLCSEV-GDALLSEETYNTRLRMLVKYFTTDYEDMHFCYMAKYVFCEVLNFLISVVNIIVLEVF 255
            :.:...: |...:.::....|...::|||.... :.|..|...|.|||:|||:..:|||.:::.|
  Fly   144 RMITDGLRGMVSVPDDYRRDRQDRILKYFVNSL-NTHNGYSFAYFFCELLNFINVIVNIFMVDKF 207

  Fly   256 LNGFWSKYLRALATIPFYDWDRWNRVSS--SVFPKIAKCEVLKFGGSGTANVMDNLCILPLNILN 318
            |.|.:..|  ....:.|.:.|:..|...  .:||::.||...|||.||:....|.||:|.|||||
  Fly   208 LGGAFMSY--GTDVLKFSNMDQDKRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILN 270

  Fly   319 EKIFVFLWAWFLLMALMSGLNLLCRLAMICSRYLREQMIRSQLRFMTKRHVKRALRDLTIGDWFL 383
            |||::|||.||:::|.:||:.:|..|.:|.....||.:|:...|...::.:...:|.|.|||:.:
  Fly   271 EKIYIFLWFWFIILATISGVAVLYSLVVIMMPTTRETIIKRSYRSAQRKEIAGLVRRLEIGDFLI 335

  Fly   384 MMKVSVNVNPMLFRDLMQELCEL----RTSASGSTLE 416
            :..:|.|::...:.|::|:||.|    ||.::.||||
  Fly   336 LHFLSQNLSTRSYSDMLQQLCGLLGASRTPSAPSTLE 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Inx5	NP_573353.2	Innexin	21..405	CDD:279248	119/388 (31%)
Inx3	NP_001263050.1	Innexin	26..356	CDD:279248	118/388 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3133
eggNOG	1	0.900	-	-		E1_2BWHM
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D323554at33208
OrthoFinder	1	1.000	-	-		FOG0003274
OrthoInspector	1	1.000	-	-		mtm4755
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X282
	9	8.970