DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Inx5 and Inx2

DIOPT Version :9

Sequence 1:	NP_573353.2	Gene:	Inx5 / 32901	FlyBaseID:	FBgn0030989	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001162684.1	Gene:	Inx2 / 31646	FlyBaseID:	FBgn0027108	Length:	367	Species:	Drosophila melanogaster

Alignment Length:	405	Identity:	130/405 - (32%)
Similarity:	216/405 - (53%)	Gaps:	61/405 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFSAVKPLSKYLQFKSIRIYDSVFTIHSRCTVVILLTCSLLLSARQYFGDPIQCISEEKNIEYIQ 65
            :|.:||.|   |:...:.|.::||.:|.:.||:||:..|||:::|||.||||.||.:|..:..:.
  Fly     4 VFGSVKGL---LKIDQVCIDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMD 65

  Fly    66 SYCWTMGTYILKLDDFGDQEQALVSPNQEVSYNSAFFSSATTNAPQSSSRVRTRPHFRSSLRRIG 130
            :|||...|:.:.....|...:.:|.|
  Fly    66 TYCWIYSTFTVPERLTGITGRDVVQP--------------------------------------- 91

  Fly   131 EYNEAYARSLSIAEGVGPEIRGQTERQYLRYYQWVIILLLFQSFVFYFPSCLWKVWEGRRLKQLC 195
                          |||..:.|:.|.:|.:|||||..:|.||:.:||.|..|||.|||.|||.|.
  Fly    92 --------------GVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSWEGGRLKMLV 142

  Fly   196 SEVGDALLSEETYNTRLRMLVKYFTTDYEDMHFCYMAKYVFCEVLNFLISVVNIIVLEVFLNGFW 260
            .::...::::|..|.|.::||.||..:. :.|..|..::..||.|||:..:..|..::.||:|.:
  Fly   143 MDLNSPIVNDECKNDRKKILVDYFIGNL-NRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEF 206

  Fly   261 SKYLRALATIPFYDWDRWNRVS--SSVFPKIAKCEVLKFGGSGTANVMDNLCILPLNILNEKIFV 323
            |.|  ....:.|.:.:...|:.  :.||||:.||...|:|.||:....|.||:|||||:||||:|
  Fly   207 STY--GSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYV 269

  Fly   324 FLWAWFLLMALMSGLNLLCRLAMICSRYLREQMIRSQLRFMTKRHVKRALRDLTIGDWFLMMKVS 388
            |||.||:::::|||::|:.|:|::....||..::|::.|......|:.......||||||:.::.
  Fly   270 FLWFWFIILSIMSGISLIYRIAVVAGPKLRHLLLRARSRLAESEEVELVANKCNIGDWFLLYQLG 334

  Fly   389 VNVNPMLFRDLMQEL 403
            .|::|:::::::.:|
  Fly   335 KNIDPLIYKEVISDL 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Inx5	NP_573353.2	Innexin	21..405	CDD:279248	124/385 (32%)
Inx2	NP_001162684.1	Innexin	1..351	CDD:295599	130/405 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3133
eggNOG	1	0.900	-	-		E1_2BWHM
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D323554at33208
OrthoFinder	1	1.000	-	-		FOG0003274
OrthoInspector	1	1.000	-	-		mtm4755
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X282
	9	8.970