DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RhoGAP18B and Chn2

DIOPT Version :9

Sequence 1:	NP_573352.2	Gene:	RhoGAP18B / 32898	FlyBaseID:	FBgn0261461	Length:	1317	Species:	Drosophila melanogaster
Sequence 2:	NP_114473.2	Gene:	Chn2 / 84031	RGDID:	620140	Length:	468	Species:	Rattus norvegicus

Alignment Length:	203	Identity:	56/203 - (27%)
Similarity:	96/203 - (47%)	Gaps:	24/203 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1122 LFAAPLSAL-ELNMTDHPNVPRFVVDVCAYIEQPECIEQDGLYRASGNKVLVDELRKKLTHVYDP 1185
            ::...|:.| :.:.|..|    .|||:|....:...::.:||||.||....:::::.    .:|.
  Rat   274 VYCCDLTTLVKAHNTQRP----MVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKM----AFDR 330

  Fly  1186 RWLKTD-------DIHTLTSLHKQFFRELTSPLITQEAYERL---GRSLNDDAAIERMSLAFDDM 1240
            ...|.|       ||:.:|...|.:||:|..|:||.:.|.:.   .:..|.|..:|.:......:
  Rat   331 DGEKADISANIYPDINIITGALKLYFRDLPIPIITYDTYSKFIEAAKISNADERLEAVHEVLMLL 395

  Fly  1241 PEPNRSTLRFLIRHLTRVAAASASNRMPSTNLAIVWGPCLL-----SANQIQLDIGRMNMLAKVL 1300
            |..:..|||:|:.||.:|......|.|.:.||.||:||.|:     |......|:....::.::|
  Rat   396 PPAHYETLRYLMIHLKKVTMNEKDNLMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQIL 460

  Fly  1301 IENYDRIF 1308
            |||.|.:|
  Rat   461 IENEDVLF 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP18B	NP_573352.2	RhoGAP	1141..1289	CDD:279014	45/162 (28%)
Chn2	NP_114473.2	SH2_a2chimerin_b2chimerin	52..138	CDD:198215
		C1_betaCHN	210..270	CDD:410407
		RhoGAP_chimaerin	275..468	CDD:239837	55/200 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910