DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP18B and AT5G19390

DIOPT Version :9

Sequence 1:	NP_573352.2	Gene:	RhoGAP18B / 32898	FlyBaseID:	FBgn0261461	Length:	1317	Species:	Drosophila melanogaster
Sequence 2:	NP_197440.2	Gene:	AT5G19390 / 832059	AraportID:	AT5G19390	Length:	870	Species:	Arabidopsis thaliana

Alignment Length:	239	Identity:	59/239 - (24%)
Similarity:	100/239 - (41%)	Gaps:	41/239 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1107 RGQVNSLYLDEQKYPLFAAPLS-ALELNMTDHPNVPRFVVDVCAYIEQPECIEQDGLYRASGNKV 1170
            |.:.|......:|.||.:..:. .:.|.:.|....|.|:.....:||: ...:.:|:.|.|.:
plant   141 RAETNEAIEGREKRPLKSLVVGRPILLALEDIDGSPSFLEKALQFIEK-YGTKIEGILRQSAD-- 202

  Fly  1171 LVDELRKKLTHVYDPRWLKT--DDIHTLTSLHKQFFRELTSPLITQ-------EAYERLGRSLND 1226
             |:|:.:::......:...|  :|.|.:....|...|||.|..::.       |||    |..:.
plant   203 -VEEVERRVQEYEQGKTEFTFDEDPHVVGDCIKHVLRELPSSPVSASCCTALLEAY----RIESK 262

  Fly  1227 DAAIERMSLAF-DDMPEPNRSTLRFLIRHLTRVAAASASNRMPSTNLAIVWGPCLLS---ANQIQ 1287
            :|.|..:..|. :..|||||..|:.:::.:..:::.|..|||....:|....|.||.   |.:..
plant   263 EARISSLRSAIAETFPEPNRRLLQRILKMMHTISSHSHENRMNPNAVAACMAPLLLRPLLAGECD 327

  Fly  1288 L----DIGRMN---MLA------------KVLIENYDRIFHPDN 1312
            |    |.|..|   :||            .||:|:|..||..:|
plant   328 LEDDFDGGEDNSAQLLAAANAANNAQAIITVLLEDYGSIFDEEN 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP18B	NP_573352.2	RhoGAP	1141..1289	CDD:279014	40/164 (24%)
AT5G19390	NP_197440.2	PH	19..125	CDD:278594
		PH	19..125	CDD:214574
		RhoGAP	176..313	CDD:279014	35/144 (24%)
		Lzipper-MIP1	610..689	CDD:291087
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000