Protein Alignment RhoGAP18B and chn1

DIOPT Version :9

• Sequence 1: NP_573352.2
• Gene: RhoGAP18B / 32898
• FlyBaseID: FBgn0261461
• Length: 1317
• Species: Drosophila melanogaster
• Sequence 2: NP_998165.1
• Gene: chn1 / 406273
• ZFINID: ZDB-GENE-040426-1934
• Length: 459
• Species: Danio rerio
• Alignment Length: 484
• Identity: 118/484 - (24%)
• Similarity: 178/484 - (36%)
• Gaps: 120/484 - (24%)

  Fly   906 VHQRFMTRIRRPAPPPPAQLATSNTTS-----------LAPRSDDSGCSCEAEDSYNHQHNPTPA 959
            |.:.::.::::.||.|.....||...:           |..|.|.......||.||
Zfish    15 VWKSYLYQLQQEAPHPRRVTCTSEVENRPKYYGREYHGLISREDGDLLLSVAEGSY--------- 70

  Fly   960 IPKPLKEEWERAVLAAGAVAGKRGVAPRTGRKLRVRSNARLLLTDSVLAWRETLQDVNCCEDEED 1024
                |..|.:|.       .|...:|.|.|.:.|   |.||..........:..:.::      |
Zfish    71 ----LIRESQRQ-------PGTYTLALRFGNQTR---NFRLFYDGKHFVGEKRFESIH------D 115

  Fly  1025 MIVPVTDILRAQQIQEDNEVQQTQQSTILQRYKSVSIGNL-------------LDLPGEDDKKSI 1076
            :   |||.|....| |....:...:.||...|:.|....|             .|||  |.|.|.
Zfish   116 L---VTDGLITLYI-ETKAAEYISKMTINPIYEHVGYTTLNREPALKKTLPVCKDLP--DGKHSP 174

  Fly  1077 KNRMRMKFAVNSNVFRI-----NRSPKSEK----KSRSRRGQVNSLYLDEQKYPLFAAPLSALEL 1132
            .....::..:.|.|.|.     .|.||.||    |..:.||.....|.....:.|.|..:...:.
Zfish   175 AEDSGLEERLTSLVRRATLKESERVPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADC 239

  Fly  1133 NMTDHPN----VPR-----------------------------FVVDVCAYIEQPECIEQDGLYR 1164
            .:..|..    ||.                             .|||:|....:...::.:||||
Zfish   240 GLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHNAKRPMVVDMCIREIEARGLQSEGLYR 304

  Fly  1165 ASGNKVLVDELRKKLTHVYDPRWLKTD-------DIHTLTSLHKQFFRELTSPLITQEAYERL-- 1220
            .||...|::::  ||:  :|....|.|       ||:.::...|.:||:|..|:||.:||.|.
Zfish   305 ISGFSDLIEDV--KLS--FDRDGEKADISVNVYEDINVISGALKLYFRDLPIPVITYDAYPRFIQ 365

  Fly  1221 GRSLND-DAAIERMSLAFDDMPEPNRSTLRFLIRHLTRVAAASASNRMPSTNLAIVWGPCLLSAN 1284
            ...|.| |..:|.:..|...:|..:..|||:|:.||.||......|.|.:.||.||:||.|:.|.
Zfish   366 AAKLTDPDERLEALHEALKLLPPAHCETLRYLMAHLKRVTQNEKDNLMNAENLGIVFGPTLMRAP 430

  Fly  1285 QIQL-----DIGRMNMLAKVLIENYDRIF 1308
            .:..     ||.....:.::||:|.|.:|
Zfish   431 DLDAMTALNDIRYQRQVVELLIKNEDILF 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP18B	NP_573352.2	RhoGAP	1141..1289	CDD:279014	53/191 (28%)
chn1	NP_998165.1	SH2_a2chimerin_b2chimerin	42..128	CDD:198215	24/118 (20%)
		C1_1	206..258	CDD:278556	9/51 (18%)
		RhoGAP_chimaerin	266..459	CDD:239837	58/196 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000