Protein Alignment RhoGAP18B and rrc-1

DIOPT Version :10

• Sequence 1: NP_573352.2
• Gene: RhoGAP18B / 32898
• FlyBaseID: FBgn0261461
• Length: 1317
• Species: Drosophila melanogaster
• Sequence 2: NP_001024683.1
• Gene: rrc-1 / 181195
• WormBaseID: WBGene00009800
• Length: 759
• Species: Caenorhabditis elegans
• Alignment Length: 351
• Identity: 89/351 - (25%)
• Similarity: 154/351 - (43%)
• Gaps: 77/351 - (21%)

  Fly  1021 DEEDMIVPVTDILRAQQIQEDNEVQQTQQSTILQRYKSVSIGNLLDL-------PGEDD----KK 1074
            :|..:.||.   :.|..:.:|.|..::.|..:       .:|:::.:       |.|..    |.
 Worm   157 EETSINVPA---IAAAVVTKDFEPTESSQLRL-------RVGDIVSITEMSTASPSEQTFWKAKL 211

  Fly  1075 SIKNRMRMKFAVNSNV---FRINRSPK----------------SEKK--SRSRRGQVNSLYLDEQ 1118
            :|.|:   |.....|.   |.|...|:                :|:|  :|:.|..:.:::.:.:
 Worm   212 TISNQ---KIVDPQNARLGFEIGYFPRDCVMLIDDKRLPNPLNNEQKASTRNARRYMTTMFRNRR 273

  Fly  1119 KYPLFAAPLSALELNMTDHPNVPRFVVDVCAYIEQPECIEQDGLYRASGNKVLVDELRKKL---- 1179
            :.|:|...|:  :|.|.....||..|...||.||....:  .|:||..|.:..:..||.|.
 Worm   274 REPIFGLELT--DLYMRTGKKVPVIVEKCCASIEDQGIV--TGIYRQCGIQSNIQRLRAKFDSGA 334

  Fly  1180 ---THVYDPRWLKTDDIHTLTSLHKQFFRELTSPLITQEAYERLGRSLNDDAA----IERMSLAF 1237
               .|.:..|     ||::::||.||:||:|.:||.|.:||.:|..:...:.:    :|.:..:.
 Worm   335 EPDLHEFGQR-----DIYSVSSLLKQYFRQLPNPLFTYQAYPKLIEAFEKEDSLSEKVESLRFSL 394

  Fly  1238 DDMPEPNRSTLRFLIRHLTRVAAASASNRMPSTNLAIVWGPCL------LSANQIQLDIGRMNM- 1295
            :.|||.:..|.:||:.||||:..:.:...|.|.||||||.|.|      |:.....| :..:|:
 Worm   395 ETMPEAHYRTAKFLMEHLTRLCKSKSLTDMTSKNLAIVWSPNLFRPPPTLNGADTHL-LSGLNVH 458

  Fly  1296 --LAKVLIENYDRIF--HPDNERLVC 1317
              :....|||.:.:|  ..|.|:..|
 Worm   459 TAICDFFIENSESLFVNDIDEEQSKC 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP18B	NP_573352.2	RhoGAP	1141..1285	CDD:459875	52/160 (33%)
rrc-1	NP_001024683.1	PX_domain	41..146	CDD:470617
		SH3	168..238	CDD:473055	15/79 (19%)
		RhoGAP	276..466	CDD:470621	60/199 (30%)