DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP18B and chin-1

DIOPT Version :9

Sequence 1:	NP_573352.2	Gene:	RhoGAP18B / 32898	FlyBaseID:	FBgn0261461	Length:	1317	Species:	Drosophila melanogaster
Sequence 2:	NP_497323.3	Gene:	chin-1 / 175268	WormBaseID:	WBGene00015267	Length:	421	Species:	Caenorhabditis elegans

Alignment Length:	152	Identity:	40/152 - (26%)
Similarity:	75/152 - (49%)	Gaps:	12/152 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly  1144 VVDVCAYIEQPECIEQDGLYRASGNKVLVDELRKKLTHVYDPRWLKTDDIHTLTSLHKQFFRELT 1208
            :|.:|....:...::.:|:||.||:...:::|:::.............||||:..|.|.:||.|.
Worm   250 IVPLCIGEVESRGLDVEGIYRVSGSYDHMEKLKQQFDSNQYVDLATVCDIHTVCGLLKLYFRLLP 314

  Fly  1209 SPLITQEAYERL--------GRSLND-DAAIERMSLAFDDMPEPNRSTLRFLIRHLTRVAAASAS 1264
            ..||....:::|        .||.:: :..|.::.:   ::.:.|..||..::.||.:||..||.
Worm   315 QQLIPFSVHKQLLVAYQETNQRSTHERERQIRKVMM---ELSDANIITLGAVLAHLKKVADHSAK 376

  Fly  1265 NRMPSTNLAIVWGPCLLSANQI 1286
            |:|...|||.::.|.|..:..|
Worm   377 NKMTVENLATIFSPTLFCSGSI 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP18B	NP_573352.2	RhoGAP	1141..1289	CDD:279014	40/152 (26%)
chin-1	NP_497323.3	SH2_a2chimerin_b2chimerin	43..130	CDD:198215
		C1_1	172..224	CDD:278556
		RhoGAP	248..413	CDD:238090	40/152 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910