Protein Alignment RhoGAP18B and arhgap9

DIOPT Version :9

• Sequence 1: NP_573352.2
• Gene: RhoGAP18B / 32898
• FlyBaseID: FBgn0261461
• Length: 1317
• Species: Drosophila melanogaster
• Sequence 2: XP_005172184.2
• Gene: arhgap9 / 100334461
• ZFINID: ZDB-GENE-110510-2
• Length: 855
• Species: Danio rerio
• Alignment Length: 1103
• Identity: 219/1103 - (19%)
• Similarity: 377/1103 - (34%)
• Gaps: 358/1103 - (32%)

  Fly   297 GPWQQPKSVPARDPSSSAEE--STVTLRRSTEESAKCADEQAKLVKDFKRKLQQKRAHNVEPERE 359
            |.|::...:|:...|.|...  |||.|....:.|.:.||.:...:.:.:|.|..|:.:  ....:
Zfish    15 GSWRRGTIIPSAGTSGSGSRLASTVILEAQYDYSYRGADGRLVSIHEGERFLLLKKTN--ADWWQ 77

  Fly   360 QRRCAITANFVNDYLSALGEEKEAVQHQQVAAIEEHVAVVAIAIQPQVSVSLLRLMQSLALSASL 424
            .||..:.|.....|:.|                       ...|:..||.....|..|.:.|...
Zfish    78 ARRIGMGAKVKPIYVPA-----------------------TYVIELPVSSFRTSLPNSQSASERF 119

  Fly   425 HVSVRGFL--------TAYDKSFSLWLWHQQQQQRQQPPIN---GYRRRRARDSVVGVVGDWRRR 478
            .:..||.|        :..||.|.          |....:|   ....::|..:..      |..
Zfish   120 QMISRGSLMPCMHTHGSVPDKQFC----------RSMENLNCSSALMEKQASGAAA------RAH 168

  Fly   479 LPLFAFSFAGGNDRSVASASVS-----VSPAISESVDVCAAAASRRRANRSTRRRGTAIVREEGV 538
            .|:..||       ..|||.::     :||                         |..|.|
Zfish   169 FPMLPFS-------GSASAQLTLPGGLLSP-------------------------GAPIAR---- 197

  Fly   539 CGGESSTSSNNSKKNNNNNSNNNSGALMAAPKPNGEAERPSTNSNNNTINCSSNNNNDNISNNNN 603
                 |.||:|..:|....|:.::            |..||.:.:...:|.::..      .:.:
Zfish   198 -----SQSSSNLPQNPYQESSRST------------ACSPSRSYSQWDMNTAAPR------RHTH 239

  Fly   604 NHHTVDNESGINNNKNNDGNANCNVNEQQQQQQQQPITQNCVIKVRRPAPKVPVRNPNTSLSNPR 668
            .|..:.:.:.|:.:         :::|..::|..:|           |:| :|.:.|..:|
Zfish   240 GHMQLSSSAYISQS---------SLSEAGRRQWSEP-----------PSP-LPGQKPLQTL---- 279

  Fly   669 QIEEEQTKPNGGKKDNLRGNSFAAENS-SPEEQEEESIYQPIWQFKTIE--PVDQEI-IEALPVE 729
            |..|:...|..|:...:  |:...|.| .|..:..::.:..  |...:.  .|.::| :.:||::
Zfish   280 QQWEQYCDPATGRCYYI--NTDTKERSWKPPRRARQTNHSQ--QVNAVHAGTVQRDIRLLSLPLQ 340

  Fly   730 GEDEEDEDEEDDDVDDEEEDLGDYDESLPSDADPDVMALQAAAVFAAGVRHKLSTSTLTKRSKMM 794
            ............|:.....|...:..|         .::|.||          |:..|:..|.|.
Zfish   341 STGSSSMHRLSPDLSYISHDANGWQLS---------QSMQRAA----------SSDALSSASSMF 386

  Fly   795 MPTP--------------------LPSPTASMDHGAWETDMEFMYSRESKEEADETLSLGSTVTN 839
            ..||                    |||...:.:   .::|...:....|.:.:.::    ..||.
Zfish   387 DDTPRRNSALSGGMAHISHSYSMILPSQRTATN---GQSDYRVVVEPPSSDSSPDS----EGVTP 444

  Fly   840 STATLGSISSTGSSVTGQPKDTPKDLPADQQPSVVVHPILRNICIFYSQKDPKKYSAIFYDYHLS 904
            .....|.::.|..:..|      :.|..:..||.||  ::.|..:|:  ||||
Zfish   445 ELEKAGLLNKTKIAEGG------RKLRKNWNPSWVV--LVGNSLVFF--KDPK------------ 487

  Fly   905 LVHQRFMTRIRRPAPPPPAQLATSNTTSLAPRSDDSGCSCEAEDSYNHQHNPTPAIPKPLKEEWE 969
                                  :.|..|..|.:.....|.:...:               :.:|
Zfish   488 ----------------------SQNPESWKPGNSRPESSVDLRGA---------------QLQW- 514

  Fly   970 RAVLAAGAVAGKRGVAPRTGRKLRVRSNARLLL---TDSVL-AWRETLQDVNCCEDEEDMIVPVT 1030
                 |..::.|:.|.     |||..:....||   |||:: .|..|:|:|....|:|:   |:.
Zfish   515 -----ANDLSSKKNVF-----KLRTITGNEFLLQSETDSLIREWYRTIQNVIDRLDKEN---PLD 566

  Fly  1031 DILRAQQIQEDNEVQQTQQSTILQRYKSVSIGNLLDLPGEDDKKSIKNRMRMKFAVNSNVFRINR 1095
            ::|...                |:|..||   .|||..|::|:.    |..:|.::..:...:..
Zfish   567 NVLLYS----------------LRRAGSV---ELLDHSGDEDEV----RGGIKASLPRSTSNLEN 608

  Fly  1096 SPKSEKKSRSRRGQVNSLYLDEQKYPLFAAPLSALE----------------LNMTDHPNVPRFV 1144
            |.....|||.:            |..|...||..|:                |...:...||:|
Zfish   609 SEHKRVKSRLK------------KLILRRPPLQTLQEKGLIKDQVFGCSLELLCEREKCTVPQF- 660

  Fly  1145 VDVCAYIEQPECIEQDGLYRASGNKVLVDELRKKLTH----------------------VYDPRW 1187
            |..|....:.:.:|.||:||.|||..::.:||..:.|                      :.||:|
Zfish   661 VRKCTEAVERKGLETDGIYRVSGNLAVIQKLRFAVNHERAVTTDGRYLFPEALVQERLDLDDPQW 725

  Fly  1188 LKTDDIHTLTSLHKQFFRELTSPLITQEAYERLGRSL---NDDAAIERMSLAFDDMPEPNRSTLR 1249
               :|||.:|...|.|||||..||:...|:.....|:   :....:||:.:....:|..|:.||:
Zfish   726 ---EDIHVITGALKLFFRELPEPLVPFSAFHDFVDSIKIADHLERVERLKMLVLSLPPANQHTLQ 787

  Fly  1250 FLIRHLTRVAAASASNRMPSTNLAIVWGPCLL----SANQIQLDIGRMNMLAKVLIENYDRIF 1308
            .:||||.||...|.||||.:.|:.||:||.|:    .:..:..::...|...:.|:..|..||
Zfish   788 HMIRHLRRVMERSDSNRMSTQNIGIVFGPTLMRPENESGNMAFNMVYQNQAIETLLSQYQHIF 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP18B	NP_573352.2	RhoGAP	1141..1289	CDD:279014	55/176 (31%)
arhgap9	XP_005172184.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000816
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000