Protein Alignment RhoGAP18B and arhgap15

DIOPT Version :10

• Sequence 1: NP_573352.2
• Gene: RhoGAP18B / 32898
• FlyBaseID: FBgn0261461
• Length: 1317
• Species: Drosophila melanogaster
• Sequence 2: NP_001122027.1
• Gene: arhgap15 / 100003547
• ZFINID: ZDB-GENE-070912-314
• Length: 465
• Species: Danio rerio
• Alignment Length: 529
• Identity: 111/529 - (20%)
• Similarity: 196/529 - (37%)
• Gaps: 138/529 - (26%)

  Fly   837 VTNSTATLGS-ISSTGSSVTGQPKDTPKDL--------PADQQPSVVVHPILR------------ 880
            :.||.::.|. :|.|.|.|..:.:...|.:        ..:.:.||.:.|:|:
Zfish    17 IKNSQSSTGERLSQTKSMVLPEAETLQKPINRHRRNQSQHNSEVSVGLQPVLKGEYLNKAKIAEG 81

  Fly   881 -----------------NICIFYSQKDPKKYSAIFYDYHLSLVHQRFMTRIRRPAPPPPAQL--- 925
                             |..:||  |:.|               |..::.::....|....|
Zfish    82 GKKLRKNWTLTWVVLSSNQLLFY--KESK---------------QEAVSNLKPGGKPDGVDLNGA 129

  Fly   926 ATSNTTSLAPRSDDSGCSCEAEDSYNHQHNPTPAIPKPLKEEWERAVLAAGAVAGKRGVAPRTGR 990
            ....||..:.|.:....:......:..|.:..|.|.|     |..|:..|..:..........||
Zfish   130 VIEWTTEKSSRKNVIQITTPTGHEFLLQADHFPTISK-----WHDAIKKAVDILSSGSGGQSCGR 189

  Fly   991 KLRVRSNARLLLTDSVLAWRETLQDVNCCEDEEDMIVPVTDILRAQQIQEDNEVQQTQQSTILQR 1055
            ....|||:...|:      |.|      ||..:               .:..|.:...:.:|:.:
Zfish   190 AALHRSNSTECLS------RPT------CESSK---------------PKPKETKSEHRRSIMFK 227

  Fly  1056 YKSVSIGNLLDLPGED--DKKSIKNRMRMKFAVNSNVFRINRSPKSEKKSRSRRGQVNSLYLDEQ 1118
                     |:....|  ||..:|||:: ||        |:|.|  ..|:...:|.:
Zfish   228 ---------LNYSASDSADKNGVKNRLK-KF--------ISRRP--SMKTLQEKGII-------- 264

  Fly  1119 KYPLFAAPLSALELNMTDHPNVPRFVVDVCAYIEQPECIEQDGLYRASGNKVLVDELR-----KK 1178
            |..:|...:  |.|...:...||:| |.:|....:...:|.||:||.|||..::.:||     ::
Zfish   265 KDRVFGCHM--LTLCDREKTTVPKF-VKLCVEEVEKRGLEADGIYRVSGNLAIIQKLRFLVDQEE 326

  Fly  1179 LTHVYDPRWLKTDDIHTLTSLHKQFFRELTSPLITQEAYERLGRSL---NDDAAIERMSLAFDDM 1240
            ...:.|.:|   :|||.:|...|.|||||..||.....::....::   .....::.|......:
Zfish   327 ELDLGDSQW---EDIHVITGALKMFFRELPEPLFPFRFFDLFVETIKIKEPTQKVQAMKKLIHQL 388

  Fly  1241 PEPNRSTLRFLIRHLTRVAAASASNRMPSTNLAIVWGPCLL----SANQIQLDIGRMNMLAKVLI 1301
            |:||.:|::.|..||.||...|..|.|.:..::||:||.|:    .:..:::::...|.:.:.::
Zfish   389 PKPNHNTMKLLFHHLRRVLTKSQKNLMSTQGVSIVFGPTLMWPEFESGNMEVNMVYQNQIVECIL 453

  Fly  1302 ENYDRIFHP 1310
            .....||.|
Zfish   454 IGCVEIFGP 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP18B	NP_573352.2	RhoGAP	1141..1285	CDD:459875	46/155 (30%)
arhgap15	NP_001122027.1	PH_ARHGAP9-like	68..176	CDD:270053	19/129 (15%)
		RhoGAP_ARHGAP27_15_12_9	269..453	CDD:239868	51/189 (27%)