back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tgy and LFNG

DIOPT Version :10

Sequence 1:	NP_573349.4	Gene:	tgy / 32896	FlyBaseID:	FBgn0030984	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001035257.1	Gene:	LFNG / 3955	HGNCID:	6560	Length:	379	Species:	Homo sapiens

Alignment Length:	269	Identity:	59/269 - (21%)
Similarity:	99/269 - (36%)	Gaps:	71/269 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 LAEKM-HREVRVLCWVLTTPKYHKTRAIHVLRTWGKRCNKIYFMTSEPDDE-----LPTVVLTKP 147
            |||.: .|:|.:.  |.||.|:|:.|...:|.||..|..::.|:.::.:||     ...||:|..
Human   106 LAEPLAPRDVFIA--VKTTKKFHRARLDLLLETWISRHKEMTFIFTDGEDEALARHTGNVVITNC 168

  Fly   148 DRYEMLWGKTKEAFVHIHEQMRHEADWFIKADDDTYLFLENLRYMLYPYSPETPIYFG---FNYK 209
            .........:.:..|.....:.....||...|||.|:.|..|..:|..|.....:|.|   .:..
Human   169 SAAHSRQALSCKMAVEYDRFIESGRKWFCHVDDDNYVNLRALLRLLASYPHTRDVYVGKPSLDRP 233

  Fly   210 MVGTHQKNES--------YMSGGSGYVLSRE-ALRI--FAEG---VNDTTKCRQEDD-------- 252
            :....:.:|:        :.:||:|:.:||. ||::  :|.|   :|...:.|..||
Human   234 IQAMERVSENKVRPVHFWFATGGAGFCISRGLALKMSPWASGGHFMNTAERIRLPDDCTIGYIVE 298

  Fly   253 -------------HA--------------EDVEMGKCLFN-----------LGVKAGDSRDEQLR 279
                         |:              |.|.:...:|.           ..|:|..||...:.
Human   299 ALLGVPLIRSGLFHSHLENLQQVPTSELHEQVTLSYGMFENKRNAVHVKGPFSVEADPSRFRSIH 363

  Fly   280 NRFYPIAPY 288
            ...||..|:
Human   364 CHLYPDTPW 372

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.