DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and SSH2

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001269058.1	Gene:	SSH2 / 85464	HGNCID:	30580	Length:	1450	Species:	Homo sapiens

Alignment Length:	151	Identity:	44/151 - (29%)
Similarity:	73/151 - (48%)	Gaps:	20/151 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 EVYPGIYIGDAAAAKNKTYLRLMGITHVLNAAEGCRYGQVDTGHSYYRDMPSIRRSHKDCVFRYM 137
            :::..:::|....|.|...|:..|:.::||...     ::|   :::   |.        ||.|.
Human   337 QIFEHVFLGSEWNASNLEDLQNRGVRYILNVTR-----EID---NFF---PG--------VFEYH 382

  Fly   138 GFPMVDAPTTDISRYFYVASKFIDSAISSGGKILVHCLVGMSRSATCVLAYLMICRKMSAVDAIR 202
            ...:.|...||:..|:....|||..|...|.|.||||.:|:||||:.|:||.|.....:...|..
Human   383 NIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYD 447

  Fly   203 TVRMRRDI-RPNDGFLQQLAD 222
            .|:.||.: :||..|::||.:
Human   448 YVKERRTVTKPNPSFMRQLEE 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	44/151 (29%)
SSH2	NP_001269058.1	SSH-N	38..263	CDD:212166
		DEK_C	278..329	CDD:285919
		DSPc	335..470	CDD:238073	44/151 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	644..668
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	691..711
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	723..755
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	824..852
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	867..889
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	904..981
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	989..1008
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1046..1068
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1097..1135
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1171..1206
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820