DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and DUSP16

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_085143.1	Gene:	DUSP16 / 80824	HGNCID:	17909	Length:	665	Species:	Homo sapiens

Alignment Length:	193	Identity:	62/193 - (32%)
Similarity:	88/193 - (45%)	Gaps:	35/193 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 SRALPGLRRAECA------------IHDVDCDEVYPGIYIGDAAAAKNKTYLRLMGITHVLNAAE 105
            ||..|||...:..            :.::....:.|.:|:|......||..::..||.:||||:.
Human   129 SRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASN 193

  Fly   106 GCRYGQVDTGHSYYRDMPS-IRRSHKDCVFRYMGFPMVDAPTTDISRYFYVASKFIDSAISSGGK 169
            .|             ..|. |..||      ::..|:.|:....|..:...:..||:.|.:|.|.
Human   194 TC-------------PKPDFIPESH------FLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGC 239

  Fly   170 ILVHCLVGMSRSATCVLAYLMICRKMSAVDAIRTVRMRR-DIRPNDGFLQQLADLDMELKRKN 231
            :|||||.|:|||||..:||:|....||..:|.|.|:.:| .|.||..||.||  ||.|.|.||
Human   240 VLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQL--LDYEKKIKN 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	53/157 (34%)
DUSP16	NP_085143.1	DSP_MapKP	10..136	CDD:238723	4/6 (67%)
		DSPc	158..295	CDD:238073	53/157 (34%)
		CDC14	<207..300	CDD:225297	39/94 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	321..368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	449..505
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	597..665
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820