DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and DUSP26

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001292044.1	Gene:	DUSP26 / 78986	HGNCID:	28161	Length:	211	Species:	Homo sapiens

Alignment Length:	231	Identity:	85/231 - (36%)
Similarity:	123/231 - (53%)	Gaps:	31/231 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SWRYALLTDRYSSSIGDRYSPHYYQSPSRLETSEQTTGRQLQRVLH--YSMAPSRALPGLRRAEC 64
            :|.:|.:|          :...:.:|.||.....:.|..::..|.|  .::.....|....:..|
Human     5 NWLWASMT----------FMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTAC 59

  Fly    65 AIHDVDCDEVYPGIYIGDAAAAKNKTYLRLMGITHVLNAAEGCRYGQVDTGHSYYRDMPSIRRSH 129
            .    ..|||:||:|:||...|.|:..||.:||||||||:           ||.:|..|   .::
Human    60 N----HADEVWPGLYLGDQDMANNRRELRRLGITHVLNAS-----------HSRWRGTP---EAY 106

  Fly   130 KDCVFRYMGFPMVDAPTTDISRYFYVASKFIDSAISS-GGKILVHCLVGMSRSATCVLAYLMICR 193
            :....||:|....|:|..|:|.:|..|:.||..|:|. ||||||||.||:|||||.||||||:..
Human   107 EGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYH 171

  Fly   194 KMSAVDAIRTVRMRRDIRPNDGFLQQLADLDMELKR 229
            .::.|:||:.|:..|.|.||.|||:||..||..|::
Human   172 HLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLRQ 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	73/156 (47%)
DUSP26	NP_001292044.1	DUSP26	62..205	CDD:350426	73/156 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	123	1.000	Domainoid score	I5579
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H11421
Inparanoid	1	1.050	135	1.000	Inparanoid score	I4582
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45754
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	1	1.000	-	-		FOG0000750
OrthoInspector	1	1.000	-	-		otm41148
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45682
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X520
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.980