DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7378 and STYX

DIOPT Version :9

Sequence 1:NP_001285421.1 Gene:CG7378 / 32888 FlyBaseID:FBgn0030976 Length:235 Species:Drosophila melanogaster
Sequence 2:NP_001124173.1 Gene:STYX / 6815 HGNCID:11447 Length:223 Species:Homo sapiens


Alignment Length:158 Identity:53/158 - (33%)
Similarity:86/158 - (54%) Gaps:17/158 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 DCDEVYPGIYIGD-AAAAKNK-TYLRLMGITHVLNAAEGCRYGQVDTGHSYYRDMPSIRRSHKDC 132
            :..|:.||:::|. ::|.|:| ..|:..||||::     |....::....    .|:.::     
Human    28 EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHII-----CIRQNIEANFI----KPNFQQ----- 78

  Fly   133 VFRYMGFPMVDAPTTDISRYFYVASKFIDSAISSGGKILVHCLVGMSRSATCVLAYLMICRKMSA 197
            :|||:...:.|.|..:|.|:|.:..:|||.::..|||:|||...|:||||..|:||:|....|..
Human    79 LFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKY 143

  Fly   198 VDAIRTVRMRR-DIRPNDGFLQQLADLD 224
            .||...|:.|| .|.||.||:.||.:.:
Human   144 RDAFAYVQERRFCINPNAGFVHQLQEYE 171

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7378NP_001285421.1 DUSP3-like 71..227 CDD:350365 53/157 (34%)
STYXNP_001124173.1 DSP_STYX 25..175 CDD:350372 53/158 (34%)
Interaction with FBXW7. /evidence=ECO:0000269|PubMed:28007894 76..78 0/1 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 197..223
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1716
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1576308at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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