DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and si:ch211-121a2.2

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001098581.1	Gene:	si:ch211-121a2.2 / 564515	ZFINID:	ZDB-GENE-070705-21	Length:	449	Species:	Danio rerio

Alignment Length:	222	Identity:	81/222 - (36%)
Similarity:	107/222 - (48%)	Gaps:	46/222 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 PHYYQSPSRLETSEQTTGRQLQRVLHYSMAPSRALPGLRRAECAIHDVDCDEVYPGIYIGDAAAA 86
            |...:|..|:|          :.|:|......:         |.:......||:|.:.|||...|
Zfish   254 PEPQESKQRIE----------ETVIHLKHCLQK---------CTLDQTSATEVWPSVVIGDEHTA 299

  Fly    87 KNKTYLRLMGITHVLNAAEGCRYG---------------QVDTGHSYYRDMPSIRRSHKDCVFRY 136
            .::..|:..||||:|||| ..::.               :|.||..||:.|.          ..|
Zfish   300 MDRAKLKQRGITHILNAA-AIKHNLMASLGMPRKEDLLRKVKTGAQYYKGMN----------ITY 353

  Fly   137 MGFPMVDAPTTDISRYFYVASKFIDSAISS-GGKILVHCLVGMSRSATCVLAYLMICRKMSAVDA 200
            .|.|:||.|..|||:|||.::.||..|:|. ..|:||||..|:|||.|..||||||.||||..||
Zfish   354 YGVPVVDDPLFDISKYFYPSAAFIHQALSEPENKVLVHCSDGVSRSPTLFLAYLMIHRKMSVEDA 418

  Fly   201 IRTVRMRRDIRPNDGFLQQLADLDMEL 227
            |..|...|.|.||.|||:|||.|:.:|
Zfish   419 IGHVLKVRCIWPNLGFLKQLAVLNSKL 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	73/171 (43%)
si:ch211-121a2.2	NP_001098581.1	CDC14	61..244	CDD:225297
		DSPc	80..223	CDD:238073
		DSPc	284..438	CDD:238073	69/164 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	1	1.000	-	-		FOG0000750
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45682
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920