DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and Styx

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_062611.2	Gene:	Styx / 56291	MGIID:	1891150	Length:	223	Species:	Mus musculus

Alignment Length:	158	Identity:	54/158 - (34%)
Similarity:	87/158 - (55%)	Gaps:	17/158 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 DCDEVYPGIYIGD-AAAAKNK-TYLRLMGITHVLNAAEGCRYGQVDTGHSYYRDMPSIRRSHKDC 132
            :..||.||:::|. ::|.|:| ..|:..||||::     |....::....    .|:.::
Mouse    28 EMQEVLPGLFLGPYSSAMKSKLPILQKHGITHII-----CIRQNIEANFI----KPNFQQ----- 78

  Fly   133 VFRYMGFPMVDAPTTDISRYFYVASKFIDSAISSGGKILVHCLVGMSRSATCVLAYLMICRKMSA 197
            :|||:...:.|.|..:|.|:|.:..:|||.::.:|||:|||...|:||||..|:||:|....|..
Mouse    79 LFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQNGGKVLVHGNAGISRSAAFVIAYIMETFGMKY 143

  Fly   198 VDAIRTVRMRR-DIRPNDGFLQQLADLD 224
            .||...|:.|| .|.||.||:.||.:.:
Mouse   144 RDAFAYVQERRFCINPNAGFVHQLQEYE 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	54/157 (34%)
Styx	NP_062611.2	DSP_STYX	25..175	CDD:350372	54/158 (34%)
		Interaction with FBXW7. /evidence=ECO:0000250\|UniProtKB:Q8WUJ0	76..78		0/1 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	199..223
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820