DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and Ssh3

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001361616.1	Gene:	Ssh3 / 245857	MGIID:	2683546	Length:	653	Species:	Mus musculus

Alignment Length:	217	Identity:	57/217 - (26%)
Similarity:	92/217 - (42%)	Gaps:	47/217 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SRLETSEQTTGRQLQRVLHYSMAPSRALPGLRRA-----ECAIHD----VD------------CD 72
            |..|..||....:|.:||..|...|.....:|:|     .|.:..    :|            ..
Mouse   267 SEQEKMEQAILAELWQVLDTSDLDSVTSKEIRQALELRLGCPLQQYRDFIDNQMLLLMAQQDRAS 331

  Fly    73 EVYPGIYIGDAAAAKNKTYLRLMGITHVLNAAEGCRYGQVDTGHSYYRDMPSIRRSHKDCVFRYM 137
            .::|.:|:|....|.|...|:...::|:||.|.     ::|   :::.:.           |.|.
Mouse   332 RIFPHLYLGSEWNAANLEELQKNRVSHILNMAR-----EID---NFFPER-----------FTYY 377

  Fly   138 GFPMVDAPTTDISRYFYVASKFIDSAISSGGKILVHCLVGMSRSATCVLAYLMICRKMSAVD--- 199
            ...:.|..:..:..::....:||:.|.:.|.::||||.:|:||||..||||.|   |....|
Mouse   378 NVRVWDEESAQLLPHWKETHRFIEDARAQGTRVLVHCKMGVSRSAATVLAYAM---KQYGWDLEQ 439

  Fly   200 -AIRTVRMRRDIRPNDGFLQQL 220
             .|....:|..:|||.|||:||
Mouse   440 ALIHVQELRPIVRPNHGFLRQL 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	44/154 (29%)
Ssh3	NP_001361616.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		SSH-N	3..256	CDD:212166
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	49..90
		DEK_C	273..324	CDD:370106	11/50 (22%)
		DSP_slingshot_3	327..470	CDD:350419	44/157 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	545..590
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	612..653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820