DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and Dusp27

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001028516.2	Gene:	Dusp27 / 240892	MGIID:	2685055	Length:	1138	Species:	Mus musculus

Alignment Length:	214	Identity:	78/214 - (36%)
Similarity:	123/214 - (57%)	Gaps:	27/214 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QSPSRLETSEQTT-----GRQLQRVLHYSMAPSRALPGLRRA------ECAIHDVDCDEVYPGIY 79
            :.|..||::||..     .|..:::...|:..:..:..|:||      |...::|  |||:|.::
Mouse    80 ECPGMLESAEQLLVEDLYNRVREKMDDRSLFNTPCVLDLQRALTQDRQEAPRNEV--DEVWPNVF 142

  Fly    80 IGDAAAAKNKTYLRLMGITHVLNAAEGCRYGQVDTGHSYYRDMPSIRRSHKDCVFRYMGFPMVDA 144
            |.:.:.|.||..|:.:||||:||||.|.   .|.||..:|..:.          .:|:|..:.|.
Mouse   143 IAEKSVAVNKGRLKRLGITHILNAAHGT---GVYTGSEFYTGLE----------IQYLGVEVDDF 194

  Fly   145 PTTDISRYFYVASKFIDSA-ISSGGKILVHCLVGMSRSATCVLAYLMICRKMSAVDAIRTVRMRR 208
            |..|||::|..|::|:|.| ::..||:||...:|:||||..|:|||||...|:.::|:.|||.:|
Mouse   195 PEVDISQHFRKAAEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHSMAILEALMTVRRKR 259

  Fly   209 DIRPNDGFLQQLADLDMEL 227
            .|.||||||:||.:|:.:|
Mouse   260 AIYPNDGFLKQLRELNEKL 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	65/156 (42%)
Dusp27	NP_001028516.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		DSPc	133..275	CDD:238073	65/156 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	309..336
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	348..473
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	486..515
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	552..575
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	592..618
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	660..694
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	761..800
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	850..1117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43217
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45682
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910