DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and DUSP5

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_004410.3	Gene:	DUSP5 / 1847	HGNCID:	3071	Length:	384	Species:	Homo sapiens

Alignment Length:	158	Identity:	52/158 - (32%)
Similarity:	76/158 - (48%)	Gaps:	24/158 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 EVYPGIYIGDAAAAKNKTYLRLMGITHVLNAAEGCRYGQVDTGHSYYRDMPSIRRSHKDCV--FR 135
            |:.|.:|:|.|..|....:|..:.||.:||.:                     ||:.:.|.  ..
Human   181 EILPFLYLGSAYHASKCEFLANLHITALLNVS---------------------RRTSEACATHLH 224

  Fly   136 YMGFPMVDAPTTDISRYFYVASKFIDSAISSGGKILVHCLVGMSRSATCVLAYLMICRKMSAVDA 200
            |...|:.|:.|.|||.:|..|..|||.....|||:||||..|:|||.|..:||||..::....:|
Human   225 YKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEA 289

  Fly   201 IRTVRMRRD-IRPNDGFLQQLADLDMEL 227
            ...::.||. :.||.||:.||...:.|:
Human   290 FDYIKQRRSMVSPNFGFMGQLLQYESEI 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	51/156 (33%)
DUSP5	NP_004410.3	DSP_MapKP	5..140	CDD:238723
		Nuclear localization signal. /evidence=ECO:0000255	53..74
		DSPc	178..314	CDD:238073	51/153 (33%)
		CDC14	<227..311	CDD:225297	35/83 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820