DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and DUSP4

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001385.1	Gene:	DUSP4 / 1846	HGNCID:	3070	Length:	394	Species:	Homo sapiens

Alignment Length:	181	Identity:	57/181 - (31%)
Similarity:	86/181 - (47%)	Gaps:	24/181 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PSRALP---GLRRAECAIHDVDCD-EVYPGIYIGDAAAAKNKTYLRLMGITHVLNAAEGCRYGQV 112
            ||...|   |.......:||.... |:.|.:|:|.|..|..:..|..:|||.:||.:..|
Human   173 PSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDC----- 232

  Fly   113 DTGHSYYRDMPSIRRSHKDCVFRYMGFPMVDAPTTDISRYFYVASKFIDSAISSGGKILVHCLVG 177
                      |:....|    ::|...|:.|....|||.:|..|.::||:.....|::||||..|
Human   233 ----------PNHFEGH----YQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAG 283

  Fly   178 MSRSATCVLAYLMICRKMSAVDAIRTVRMRRD-IRPNDGFLQQLADLDMEL 227
            :|||||..|||||:.:::...:|...|:.||. |.||..|:.||...:.::
Human   284 ISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	51/157 (32%)
DUSP4	NP_001385.1	DSP_MapKP	9..158	CDD:238723
DUSP4	NP_001385.1	DSPc	195..331	CDD:238073	51/154 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820