DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and Dusp8

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_032774.1	Gene:	Dusp8 / 18218	MGIID:	106626	Length:	663	Species:	Mus musculus

Alignment Length:	190	Identity:	59/190 - (31%)
Similarity:	84/190 - (44%)	Gaps:	32/190 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 SRALPGLRRAECA-------------IHDVDCDEVYPGIYIGDAAAAKNKTYLRLMGITHVLNAA 104
            |...|||...:.|             :..|....:.|.:|:|......||..:...||::||||:
Mouse   130 SSCFPGLCEGKPATLPSMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNAS 194

  Fly   105 EGCRYGQVDTGHSYYRDMPSIRRSHKDCVFRYMGFPMVDAPTTDISRYFYVASKFIDSAISSGGK 169
            ..|             ..|..     .|..|:|..|:.|.....:..:...:.:|||.|..|..:
Mouse   195 NSC-------------PKPDF-----ICESRFMRIPINDNYCEKLLPWLDKSIEFIDKAKLSSCQ 241

  Fly   170 ILVHCLVGMSRSATCVLAYLMICRKMSAVDAIRTVRMRR-DIRPNDGFLQQLADLDMELK 228
            ::||||.|:|||||..:||:|....||:.||.|.|:.|| .|.||..||.||.:.:..||
Mouse   242 VIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLK 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	51/156 (33%)
Dusp8	NP_032774.1	DSP_MapKP	10..137	CDD:238723	3/6 (50%)
		DSP_DUSP8	150..300	CDD:350493	52/167 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	313..367
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	404..624
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820