DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7378 and DUSP10

DIOPT Version :9

Sequence 1:	NP_001285421.1	Gene:	CG7378 / 32888	FlyBaseID:	FBgn0030976	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_009138.1	Gene:	DUSP10 / 11221	HGNCID:	3065	Length:	482	Species:	Homo sapiens

Alignment Length:	163	Identity:	47/163 - (28%)
Similarity:	83/163 - (50%)	Gaps:	18/163 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 IHDVDCDEVYPGIYIGDAAAAKNKTYLRLMGITHVLNAAEGCRYGQVDTGHSYYRDMPSIRRSHK 130
            |.:.:...:.|.:::|:...|::...::.:.|.:|:|         |.|....|.        ::
Human   317 IENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVIN---------VTTHLPLYH--------YE 364

  Fly   131 DCVFRYMGFPMVDAPTTDISRYFYVASKFIDSAISSGGKILVHCLVGMSRSATCVLAYLMICRKM 195
            ..:|.|...|..|:...::.:||..|.:||:.|...|..:|:||..|:|||||.|:||||...:|
Human   365 KGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRM 429

  Fly   196 SAVDAIRTVRMRRD-IRPNDGFLQQLADLDMEL 227
            :..||.:.|:.:|. |.||..|:.||.:.:.:|
Human   430 TMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7378	NP_001285421.1	DUSP3-like	71..227	CDD:350365	45/156 (29%)
DUSP10	NP_009138.1	DSP_MapKP	149..284	CDD:238723
		Interaction with MAP kinases	199..215
		DSPc	321..459	CDD:238073	45/154 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820