DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SdhBL and SDH2-1

DIOPT Version :9

Sequence 1:	NP_001285420.1	Gene:	SdhBL / 32887	FlyBaseID:	FBgn0030975	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	NP_001118718.1	Gene:	SDH2-1 / 822359	AraportID:	AT3G27380	Length:	279	Species:	Arabidopsis thaliana

Alignment Length:	288	Identity:	153/288 - (53%)
Similarity:	191/288 - (66%)	Gaps:	29/288 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 KPGGAAAAA----AGSAKPGGASTGKPASGNAPATPPPPPPPPPAKSAPPVKAKKPRLKTFEIYR 194
            ||...|.||    |.....|..:..|.:||.                     .:...||||:|||
plant    13 KPSKLATAARLIPARWTSTGAEAETKASSGG---------------------GRGSNLKTFQIYR 56

  Fly   195 WKPGD--QPQTQTYEVDLEQCGAMVLDALIKIKNEMDPTLTFRRSCREGICGSCAMNINGTNTLA 257
            |.|.:  :|:.|.|::||:.||.|||||||||||||||:|||||||||||||||||||:|.|.||
plant    57 WNPDNPGKPELQNYQIDLKDCGPMVLDALIKIKNEMDPSLTFRRSCREGICGSCAMNIDGCNGLA 121

  Fly   258 CVSSIDQNESKCCRIYPLPHLYVVRDLVPDMSQFYDQYRSIQPWLQRKDLKREAGTAQYLQSVDD 322
            |::.| |:|:....|.||||::|::|||.||:.||:||:||:|||:|| ........:.|||..|
plant   122 CLTKI-QDEASETTITPLPHMFVIKDLVVDMTNFYNQYKSIEPWLKRK-TPASVPAKEILQSKKD 184

  Fly   323 RLVLDGLYECILCACCQTSCPSYWWNSNKYLGPAVLMQAYRWVIDSRDEATEQRLDFLKDPWKLY 387
            |..|||:|||||||||.|||||||||...|||||.|:.|.||:.|||||.|::||:.:.|.:|||
plant   185 RAKLDGMYECILCACCSTSCPSYWWNPESYLGPAALLHANRWISDSRDEYTKERLEAIDDEFKLY 249

  Fly   388 RCHSIMNCTNTCPKHLNPARAIIQLKQL 415
            |||:|:||...|||.|||.:.|..:|||
plant   250 RCHTILNCARACPKGLNPGKQITHIKQL 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SdhBL	NP_001285420.1	sdhB	189..417	CDD:235652	141/229 (62%)
		Fer2_3	189..293	CDD:289830	68/105 (65%)
		Fer4_8	330..403	CDD:289926	48/72 (67%)
SDH2-1	NP_001118718.1	PLN00129	1..279	CDD:215067	153/288 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	165	1.000	Domainoid score	I1211
eggNOG	1	0.900	-	-		E1_COG0479
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	346	1.000	Inparanoid score	I627
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264157at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm957
orthoMCL	1	0.900	-	-		OOG6_100664
Panther	1	1.100	-	-	O	PTHR11921
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1851
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830