DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Flacc and thoc2

DIOPT Version :9

Sequence 1:NP_573339.1 Gene:Flacc / 32886 FlyBaseID:FBgn0030974 Length:1150 Species:Drosophila melanogaster
Sequence 2:XP_005157191.1 Gene:thoc2 / 368417 ZFINID:ZDB-GENE-030616-54 Length:1560 Species:Danio rerio


Alignment Length:531 Identity:98/531 - (18%)
Similarity:180/531 - (33%) Gaps:161/531 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   151 HVHRSLSPTTRAKLK----KLAERKRLRAASKEQRERDKLRVVQRDRERDHHRLGSSRSPPSSST 211
            |..:.:..||...|:    .:.:.....|||..:.|..    |..|.|:...:..:::...|.::
Zfish  1182 HKEQPVRSTTTGTLQNGPGNIGKTSTTTAASAGKTEDG----VVEDSEKSKDKSQAAQKTASKNS 1242

  Fly   212 TTTTKIRIHQDIVGKRQKSPGLGSGLGGGSSSSSSRMHHQLMSREKIIIQTRARGRTPSLERERE 276
            ||..|:            |...||........|..:...:..::||...:.:..|.||..:...:
Zfish  1243 TTANKV------------SSSNGSSTPNSMKGSKEKEDKEKTTKEKKEKKEKNPGSTPEAKTGAK 1295

  Fly   277 RERERERERERERHDLSLRERDRRDRERERAEREAARDKERAEALARCQERQRERERLAREKLRR 341
            .:::.||.:|.:..| |..:..:.|:::.:.:::..:.|...:::    |:...:||.|....:.
Zfish  1296 DKQKEERSKEEKPID-SKEKTPKADKDKRKDDKKEEKSKIDGKSI----EKDWSKERDASSDSKT 1355

  Fly   342 QEEEEGGKRGGPGRDLDLPPYGSRERSLDTVERERERERSGRHVRDKRELDPYEREQEYLEERHG 406
            :|..:..|..|.|....|.|     || :.||.|||::|        |:||.:.      ...|.
Zfish  1356 KESSKLEKNAGAGSLKSLVP-----RS-EGVESEREQKR--------RKLDTHS------SPSHS 1400

  Fly   407 HGLIDEMRRYRRRDLSPMPEHYAP----RLRDPRELYSEEERERAYKRAYLDARYSSREREAWLE 467
            ..:.|.:..::...|...|.|...    :.:|..:..|::.|:|            |:|||    
Zfish  1401 SAVKDNLNDFKDSTLKHHPNHTTVLSKIKEKDDEKKESDKSRDR------------SKERE---- 1449

  Fly   468 ARELRERELQGREYRDLETEDTLYPDERERLIRDRERDRERERDRERERNIGPRGDFRPEWEREW 532
              :..:|:.:.|:|                |..|||..:|.:|.:                    
Zfish  1450 --KKEDRKDRKRDY----------------LNSDREMSQEAKRRK-------------------- 1476

  Fly   533 EEEGAGGGPGGPSGTPGRPGGFVGGPKRGKPPAHAGGGPPSQQQHHSASEPDWDADERERERERE 597
            :|.|....                        .|:....||:..|.:      |.|..:|.:...
Zfish  1477 DENGMSSS------------------------KHSKSASPSESPHSN------DKDNSKRSKSTS 1511

  Fly   598 RDRERERDREDRPDTGGGGAGGDRPSIKNEPAWLEHDQREKPRGWQQQSSNSGGDWRDNDDAPPA 662
            :|:.   |......|.||         |.|.   .||:.:..:.            ||:......
Zfish  1512 KDKS---DLAKLEKTSGG---------KKES---RHDKEKSEKK------------RDSTGTKEE 1549

  Fly   663 PSHPHPASPHH 673
            ..| |.:|..|
Zfish  1550 KKH-HKSSEKH 1559

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FlaccNP_573339.1 None
thoc2XP_005157191.1 THOC2_N 11..560 CDD:292752
Thoc2 562..636 CDD:288568
Tho2 868..1167 CDD:288156
DUF1777 1442..>1557 CDD:285811 37/226 (16%)
NP1-WLL 1442..1528 CDD:256580 29/181 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1874
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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