Protein Alignment Flacc and ZC3H13

DIOPT Version :9

• Sequence 1: NP_573339.1
• Gene: Flacc / 32886
• FlyBaseID: FBgn0030974
• Length: 1150
• Species: Drosophila melanogaster
• Sequence 2: NP_001369140.1
• Gene: ZC3H13 / 23091
• HGNCID: 20368
• Length: 1697
• Species: Homo sapiens
• Alignment Length: 1560
• Identity: 328/1560 - (21%)
• Similarity: 494/1560 - (31%)
• Gaps: 653/1560 - (41%)

  Fly     8 SLRRYKKAARHSATHSSSSDST-------SDSDSGSSSYSSTDSEQGVGGVGVGVGVPGGAGGPG 65
            |::|:..:.|...|.|.|...|       |.|...|.|.||...:|.          |.....|.
Human   341 SIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQS----------PPRHRSPM 395

  Fly    66 GSGSVHGHPHT---HGHGHH-------PRSAERHHRKKKSSRRGGSSSGD-----EPSSSRRKRD 115
            .....|.|..|   |...|.       .|..|:..|:::...:..|||.|     ||...|.:||
Human   396 REKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRD 460

  Fly   116 KRDHVQKKLVAKRNHIK---------RKLKEARLKKRAAAALSGHVHRSLSPTTRAKLKKLAERK 171
            .||...::.:.....::         |..||:|..:.:.:....|.:|.
Human   461 ARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRD---------------- 509

  Fly   172 RLRAASKEQRERDKLRVVQRDRERDHHRLGSSRSPPSSSTTTTTKIRIHQDIVGK-RQKSPGL-- 233
              |......|:.|......|...|:|.|..|||:...:.:...::..|..|.:|: |.:.|.|
Human   510 --REGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPE 572

  Fly   234 -GSGLGGGSS----SSSSRMHHQLMSR-------------------------------------- 255
             ||....||.    ||:|..|....:|
Human   573 KGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRER 637

  Fly   256 ------------------------EKIIIQ-----TRARGRTPSLE------------------- 272
                                    |||..|     .|.:||...||
Human   638 APMFYTSCCPYPLPPVFSGPAGGTEKIRDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDE 702

  Fly   273 --RERERERERERERERERHDLSLRERDR-----RDRERERA-----EREAARDKERAEALARCQ 325
              |||:|||||:|||||||.    |||||     |:.|||||     |||..||:||.......:
Human   703 RARERDRERERDRERERERE----RERDREREKERELERERAREREREREKERDRERDRDRDHDR 763

  Fly   326 ERQRERERLAREKLRRQEEEEGGKRGGPGRDLDLPPYGSRERSLDTVERERERERSGRHVRDK-R 389
            ||:||||| .|||.|.:|.||..:              .|||..:. ||||||||.....||| |
Human   764 ERERERER-DREKEREREREERER--------------ERERERER-ERERERERERARERDKER 812

  Fly   390 EL------------DPYEREQEYLEERH---GHGLIDEMRRY-------------RRRDLSPMPE 426
            |.            |..|:.:|..|:|:   ||......:||             |||:.||..:
Human   813 ERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSD 877

  Fly   427 HY---------------APRLRDPREL------------YSEEERE-------RAYKRAYLDARY 457
            .|               ..|.::.|.|            :.||:|:       |.|:...|..:.
Human   878 AYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKV 942

  Fly   458 SS----REREAWLEARELRERELQG-REYRDLETEDTLYPDERERLIRDRERDRERERDRERERN 517
            ||    ||:...||:..:|.:::.| .:..|.||.|..: ||.::    :.:.:::...:::|.:
Human   943 SSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAH-DENKK----KAKIQKKPIKKKKEDD 1002

  Fly   518 IG-PRGDFRPEWEREWEEEGAGGGPGGPSGTPGRPGGFVGGPKRGKPPAHAGGGPPSQQQHHSAS 581
            :| .||:.....|                      .|.|..||:|:.       ..|.::....|
Human  1003 VGIERGNIETTSE----------------------DGQVFSPKKGQK-------KKSIEKKRKKS 1038

  Fly   582 EPDWDADERERERERERDRERERDREDRPDTGGGGAGGDRPSIKNEPAWLE---------HDQRE 637
            :.|.|..:.|..::.::.|                 |...|.|..:...:|         .|.
Human  1039 KGDSDISDEEAAQQSKKKR-----------------GPRTPPITTKEELVEMCNGKNGILEDS-- 1084

  Fly   638 KPRGWQQQSSNSGGDWRDND--DAPPAPSHPHPASPHHHVHPRGERGSGRGFRRGGHGHGDHGER 700
                 |::...:..||.|.|  |........|.|:                           ...
Human  1085 -----QKKEDTAFSDWSDEDVPDRTEVTEAEHTAT---------------------------ATT 1117

  Fly   701 PGYRSHPPPLMTLPVQPPGGYSRGFPHKRLPYGSGRDGAALGARDGGLPGSSTFLKKHTHAPLVS 765
            ||  |.|.||.:|...||                                           |:.:
Human  1118 PG--STPSPLSSLLPPPP-------------------------------------------PVAT 1137

  Fly   766 PTQTPLLNPLLNAAKPNAAAQASAVAAATTAVAAAKAAAQSAANATTNPGI---------LAQVS 821
            .|.|.:  |...||...|||.:.:.:|.|.:.:|      :..|.|.|...         ..:|.
Human  1138 ATATTV--PATLAATTAAAATSFSTSAITISTSA------TPTNTTNNTFANEDSHRKCHRTRVE 1194

  Fly   822 KLNTVCIKQEDA---------------------------------------SEDSAGTPEL---G 844
            |:.|..:..|||                                       .:|.:|...:   |
Human  1195 KVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSG 1259

  Fly   845 AQD-SPTQSLNL----------------NQSLSSEGNPVKQELIRTSAVEGELSEIS-----DSD 887
            ::| ..|:||.:                ::|.||:....:....|.|:.|.:....|     ||.
Human  1260 SRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSR 1324

  Fly   888 DDILNK------------------------TDKVRPKN--------------------------- 901
            |.:..:                        .||..|:|
Human  1325 DRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERER 1389

  Fly   902 -----------------------------ELPTETEQEMD------------------------- 912
                                         |...|.|.|.|
Human  1390 LISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQG 1454

  Fly   913 ---TNA-----------DEVKSEALHIV---AG---HPIKGEEGDEVL--DFEEISDGELEEDAR 955
               ||.           ||.|.:..|.:   ||   .||..:|.||:|  |.|:..|.:.||  :
Human  1455 FEETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDEE--K 1517

  Fly   956 HKGIGDALGVDWQGLIAETRQQASDAQAAQQGVDRGTSAKQRWQPYRVLLDLGISFGMAG-EGYA 1019
            .....|.:.|||.||:.:..::..:..|          |..::.|..|:|.:|||..:|| |.:|
Human  1518 MPDPLDVIDVDWSGLMPKHPKEPREPGA----------ALLKFTPGAVMLRVGISKKLAGSELFA 1572

  Fly  1020 RCVMEEARQQLLQEKEQGQQRELDGDEEPPAKIPSPLLDYREFLASQQQLEPLACVQMGLRSAAV 1084
            :  ::|..|:||::.:       |.|.         |.::.           |..:.|.......
Human  1573 K--VKETCQRLLEKPK-------DADN---------LFEHE-----------LGALNMAALLRKE 1608

  Fly  1085 ERQRLVGNVCGPGSRALSARQDLRLRRQLC----GLPARECEFPRSVPIVGEGLRNLAMQMFQRR 1145
            ||..|:.|: ||..:||..|:|..:|:||.    |...:..   .|.|:|...|..|::::|:|:
Human  1609 ERASLLSNL-GPCCKALCFRRDSAIRKQLVKNEKGTIKQAY---TSAPMVDNELLRLSLRLFKRK 1669

  Fly  1146  1145
            Human  1670  1669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Flacc	NP_573339.1	None
ZC3H13	NP_001369140.1	zf-CCCH	42..63	CDD:395517
		PRK12678	343..>566	CDD:237171	54/250 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	155	1.000	Domainoid score	I4252
eggNOG	1	0.900	-	-		E1_KOG1874
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	155	1.000	Inparanoid score	I4324
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10758
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.980