DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7332 and Mindy3

DIOPT Version :9

Sequence 1:	NP_001285417.1	Gene:	CG7332 / 32885	FlyBaseID:	FBgn0030973	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_077147.2	Gene:	Mindy3 / 66960	MGIID:	1914210	Length:	444	Species:	Mus musculus

Alignment Length:	470	Identity:	204/470 - (43%)
Similarity:	297/470 - (63%)	Gaps:	38/470 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 REIKQLLWG----DNVREDVFKRWSQGFEFSKVEPSALVQKQGGPCAVIAPVQAYLLKIIIMDLP 158
            :|:.:|:||    ..:.:.:|.||:|||.||:.|.|||.|.:||||||||||||:|||.::....
Mouse     6 KELLELVWGTKSSPGLSDTIFCRWTQGFVFSESEGSALEQFEGGPCAVIAPVQAFLLKKLLFSSE 70

  Fly   159 GIKLSEISLDKSQNLLIQALCDILKNC--RAPRYRIVHLLRRRGNATEAGSTKKRSPAGEEESAL 221
            .....:.|.::.:.||...||||:::.  .:..|.:|..||            .|:|  ||.:.:
Mouse    71 KSSWRDCSEEEQKELLCHTLCDIVESAYDSSGSYCLVSWLR------------GRTP--EEAARI 121

  Fly   222 AGQAAGSSEEVEEAAEATPASVSKLSQALQLEHDMHQELSPDEFHERLHTLHFKNIAAVARYYME 286
            :|..|.||.:||.            |.||.:|     ||..:.||..:....|:.::.:....::
Mouse   122 SGSPAQSSCQVEH------------SSALAVE-----ELGFERFHALIQKRSFRTVSELKDAVLD 169

  Fly   287 NYDQLAHTYGVLLFMYSVFLTKGLELVAADISDTSEPLIHSTYGYGGQSLINLMLTGRAVAHVWD 351
            .|....:.:|||||:|||.||||:|.:...|.|.:||||...||:|.||||||:|||.||::|||
Mouse   170 QYSMWGNKFGVLLFLYSVLLTKGIENIKNSIEDANEPLIDPVYGHGSQSLINLLLTGHAVSNVWD 234

  Fly   352 NEQDVGGLKLRGICEQSDIGFITLMEEMRYCTVGSFFKNPRYPVWVMGSDTHLTVLFSNEKRLVS 416
            .:::..|::|.||.||:.:||:||||.:|||.|||:.|:|::|:|::||:|||||.|:.:..||:
Mouse   235 GDRECSGMQLLGIHEQAAVGFLTLMEALRYCKVGSYLKSPKFPIWIVGSETHLTVFFAKDMALVA 299

  Fly   417 PETPSETGRRIFKSYDPEGNNFISTTMLREVLIALNLVSEPAYVALMQKRLDPENLGIILLNAFM 481
            ||.|||..||:|::||||.|.||:.::|.:|:.||:|||:|.|:.||:.:||||.||||||..|:
Mouse   300 PEAPSEQARRVFQTYDPEDNGFIADSLLEDVMKALDLVSDPEYINLMKNKLDPEGLGIILLGPFL 364

  Fly   482 DEFFPLESRSTPDTFELMHYNGIPGSNENNKVRYYCGTAILLEGDLKSVCTSN-PMVTCLQTKWP 545
            .||||.:..|.|::|.:.||||:..||.|.||.|..|||:::..:...:.|.: |:..|||||||
Mouse   365 QEFFPDQGSSGPESFTVYHYNGLKQSNYNEKVMYVEGTAVVMGFEDPMLQTDDTPIKRCLQTKWP 429

  Fly   546 NIEINWHDGHMPSLN 560
            .||:.|.....||||
Mouse   430 YIELLWTTDRCPSLN 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7332	NP_001285417.1	DUF4205	101..>416	CDD:290609	129/320 (40%)
Mindy3	NP_077147.2	DUF4205	29..314	CDD:290609	133/315 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837092
Domainoid	1	1.000	229	1.000	Domainoid score	I2471
eggNOG	1	0.900	-	-		E1_KOG2871
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11478
Inparanoid	1	1.050	384	1.000	Inparanoid score	I2020
Isobase	1	0.950	-	0	Normalized mean entropy	S6004
OMA	1	1.010	-	-		QHG52461
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007447
OrthoInspector	1	1.000	-	-		oto93146
orthoMCL	1	0.900	-	-		OOG6_104448
Panther	1	1.100	-	-	LDO	PTHR12473
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4563
SonicParanoid	1	1.000	-	-		X5577
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740