DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp39 and usp39

DIOPT Version :9

Sequence 1:	NP_573334.1	Gene:	Usp39 / 32881	FlyBaseID:	FBgn0030969	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_002932588.1	Gene:	usp39 / 100495792	XenbaseID:	XB-GENE-853496	Length:	501	Species:	Xenopus tropicalis

Alignment Length:	490	Identity:	303/490 - (61%)
Similarity:	376/490 - (76%)	Gaps:	11/490 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 AAKRMKLEKTPANPVEEDETPSV--------FNPKYRVCPYLDTINRNLLDFDFEKLCSISLTRI 64
            |.||:|||....:..::|:...|        .:.:.|.|||||||||::|||||||||||||:.|
Frog     3 AEKRVKLEMEEEDDDDDDDERVVGKHGRYDFEDRRSRHCPYLDTINRSVLDFDFEKLCSISLSHI 67

  Fly    65 NVYACLVCGKYFQGRGTNTHAYTHSVGEAHHVFLNLHTLRFYCLPDNYEIIDSSLDDIKYVLNPT 129
            |.||||||||||||||..:|||.|||..:||||||||||:||||||||.||||||:||.|||.||
Frog    68 NAYACLVCGKYFQGRGLKSHAYIHSVQFSHHVFLNLHTLKFYCLPDNYNIIDSSLEDITYVLKPT 132

  Fly   130 FTRQEISKLDQLQPKHSRTVDGVLYLPGVVGLNNIKANDYCNVVLHALSHVGPLRDYFLQKQSYA 194
            ||:|:|..||: |.|.||..||..||||:|||||||||||.|.||.|||:|.|||:|||::::|.
Frog   133 FTKQQIGNLDK-QAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVPPLRNYFLEEENYC 196

  Fly   195 HVVRPPGDSVFTLVQRFGELMRKMWNPRNFKSHVSPHEMLQAVVLWSSKRFQITEQGDPIDFLSW 259
            .:.|||||.:|.|||||||||||:|||||||:|||||||||||||.|.|.||||:|||.:|||||
Frog   197 DIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQAVVLCSKKNFQITKQGDGVDFLSW 261

  Fly   260 FLNTLHRALKGNKHPNSSILYKIFLGEMKIYTRKMPPVELDDAAKAQLLATEEYKDQVEDKNFIY 324
            |||.|:.||.||| ...:|:..:|.|.|:|:|:|:|..:|....|.||:..|||::::.:..|:|
Frog   262 FLNALNSALGGNK-KKKTIVTDVFQGSMRIFTKKLPHPDLPSEEKEQLMQNEEYQEKMLESPFMY 325

  Fly   325 LTCDLPPPPLFTDEFRENIIPQVNLYQLLSKFNGTAEKEYKTYKANFMKRFEITRLPQFIILYIK 389
            ||.|||..||:.||..:.|||||.|:.:|.||||..||||||||.||:|||::|:||.|:|..||
Frog   326 LTLDLPTAPLYKDEKEQLIIPQVPLFSILGKFNGITEKEYKTYKENFLKRFQLTQLPPFLIFCIK 390

  Fly   390 RFTKNTFFLEKNPTIVNFPIKHVDFGDILGMRQRDKDVKDTKYNLVANIVHDGDPKKGTYRAHIL 454
            |||||.||:|||||||||||.:||..:.|. .:.....|:|.|:|:||:||||.|.:|:||.|:|
Frog   391 RFTKNNFFVEKNPTIVNFPITNVDLREYLA-EEFQSSHKNTTYDLIANVVHDGKPNEGSYRIHVL 454

  Fly   455 HKANGQWYEMQDLHVTEILPQMITLTESYIQIYER 489
            |...|:|||:|||.||:||||||||:|:||||::|
Frog   455 HHGTGKWYELQDLQVTDILPQMITLSEAYIQIWKR 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp39	NP_573334.1	Peptidase_C19M	39..488	CDD:239134	292/448 (65%)
Usp39	NP_573334.1	UCH	158..487	CDD:278850	201/328 (61%)
usp39	XP_002932588.1	Peptidase_C19M	42..488	CDD:239134	292/448 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	419	1.000	Domainoid score	I641
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13183
Inparanoid	1	1.050	619	1.000	Inparanoid score	I869
OMA	1	1.010	-	-		QHG54751
OrthoDB	1	1.010	-	-		D219856at33208
OrthoFinder	1	1.000	-	-		FOG0003552
OrthoInspector	1	1.000	-	-		oto103380
Panther	1	1.100	-	-	LDO	PTHR21646
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2428
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080