Protein Alignment CG7322 and Hsd17b14

DIOPT Version :10

• Sequence 1: NP_573333.2
• Gene: CG7322 / 32880
• FlyBaseID: FBgn0030968
• Length: 242
• Species: Drosophila melanogaster
• Sequence 2: NP_079606.3
• Gene: Hsd17b14 / 66065
• MGIID: 1913315
• Length: 273
• Species: Mus musculus
• Alignment Length: 252
• Identity: 82/252 - (32%)
• Similarity: 124/252 - (49%)
• Gaps: 24/252 - (9%)

  Fly     3 TDLAGKVILVTGAGAGIGQALVKQLASAGATVI------AVARKPEQLQQLVAFDPVHIQPLQLD 61
            |..:|||::|||...|||.|:|:....:||.|:      |..|..||......|.|..:.. :.|
Mouse     5 TRYSGKVVVVTGGSRGIGAAIVRAFVDSGAQVVFCDKDEAGGRALEQELSGTVFIPGDVTQ-ERD 68

  Fly    62 LSGWQAVREGLAKVPLLDGLVNNAGVAIIKPF---EELTEQDFDTHFDVNIKAVFNVTQSLLPRL 123
            |.  ..|.|.|::...||.:|||||..  .|.   ||.:.|.|....:||:...:.:.:..||.|
Mouse    69 LQ--TLVSETLSRFGHLDCVVNNAGYH--PPAQLPEETSAQGFRQLLEVNLLGTYTLIKLALPHL 129

  Fly   124 -KDGASIVNVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSVNPTVVLTKMG-- 185
             |...:|:|:||:..:........|.|||.|:.::||:|||:.....:|||.::|..:.|.:.
Mouse   130 RKSRGNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRHGVRVNCISPGNIWTPLWEE 194

  Fly   186 -ADNWSDPAKS---GPLLAHIPLNRFCEVQEVVDATGYLLSSKSSFVNGHHILLEGG 238
             |.:.|||..:   |.|..  ||.|..:..||. |....|:|:::|..|..:|:.||
Mouse   195 LAASTSDPRATILEGTLAQ--PLGRMGQPAEVA-AAAVFLASEATFCTGLELLVTGG 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7322	NP_573333.2	XR_like_SDR_c	1..242	CDD:187609	82/252 (33%)
Hsd17b14	NP_079606.3	Rossmann-fold NAD(P)(+)-binding proteins	1..256	CDD:473865	82/252 (33%)