DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7322 and DCXR

DIOPT Version :9

Sequence 1:	NP_001259693.1	Gene:	CG7322 / 32880	FlyBaseID:	FBgn0030968	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_057370.1	Gene:	DCXR / 51181	HGNCID:	18985	Length:	244	Species:	Homo sapiens

Alignment Length:	239	Identity:	118/239 - (49%)
Similarity:	157/239 - (65%)	Gaps:	6/239 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LAGKVILVTGAGAGIGQALVKQLASAGATVIAVARKPEQLQQLVAFDPVHIQPLQLDLSGWQAVR 69
            |||:.:||||||.|||:..|:.|.:.||.|:||:|....|..||...| .|:|:.:||..|:|..
Human     5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECP-GIEPVCVDLGDWEATE 68

  Fly    70 EGLAKVPLLDGLVNNAGVAIIKPFEELTEQDFDTHFDVNIKAVFNVTQ----SLLPRLKDGASIV 130
            ..|..|..:|.|||||.||:::||.|:|::.||..|:||::||..|:|    .|:.|...|| ||
Human    69 RALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGA-IV 132

  Fly   131 NVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSVNPTVVLTKMGADNWSDPAKS 195
            ||||..|.|:...|:.|.:||.|||.|||.:||||||.|||||:||||||:|.||...||||.|:
Human   133 NVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA 197

  Fly   196 GPLLAHIPLNRFCEVQEVVDATGYLLSSKSSFVNGHHILLEGGY 239
            ..:|..|||.:|.||:.||:|..:|||.:|....|..:.:|||:
Human   198 KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGF 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7322	NP_001259693.1	XR_like_SDR_c	1..242	CDD:187609	118/239 (49%)
DCXR	NP_057370.1	XR_like_SDR_c	1..244	CDD:187609	118/239 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143651
Domainoid	1	1.000	199	1.000	Domainoid score	I3061
eggNOG	1	0.900	-	-		E1_KOG1207
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22964
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3675
Isobase	1	0.950	-	1.057542	Normalized mean entropy	S1884
OMA	1	1.010	-	-		QHG52160
OrthoDB	1	1.010	-	-		D1051625at2759
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	1	1.000	-	-		oto91718
orthoMCL	1	0.900	-	-		OOG6_105139
Panther	1	1.100	-	-	LDO	PTHR44252
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2478
SonicParanoid	1	1.000	-	-		X1266
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	18	17.750