Protein Alignment CG7322 and DHRS4L2

DIOPT Version :10

• Sequence 1: NP_573333.2
• Gene: CG7322 / 32880
• FlyBaseID: FBgn0030968
• Length: 242
• Species: Drosophila melanogaster
• Sequence 2: NP_932349.2
• Gene: DHRS4L2 / 317749
• HGNCID: 19731
• Length: 232
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 69/204 - (33%)
• Similarity: 108/204 - (52%)
• Gaps: 25/204 - (12%)

  Fly     5 LAGKVILVTGAGAGIGQALVKQLASAGATVIAVARKPEQLQQLVAFDPVHIQPLQLDLSGW---- 65
            |..||.|||.:..|||.|:.::||...|.|:..:||.:.:.|.||    .:|...|.::|.
Human    30 LTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVA----TLQGEGLSVTGTVCHV 90

  Fly    66 --QAVREGLAKVPL-----LDGLVNNAGVAIIKPF----EELTEQDFDTHFDVNIKAVFNVTQSL 119
              ...||.|..:.:     :|.||:||.|   .||    .::||:.:|...|:|:||...:|:::
Human    91 GKAEDRERLVAMAVKLHGGIDILVSNAAV---NPFFGSLMDVTEEVWDKTLDINVKAPALMTKAV 152

  Fly   120 LPRL--KDGASIVNVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSVNPTVV-L 181
            :|.:  :.|.|:|.|||||:.....|.:.|:.:|.||..|..:||:||.||.||||.::..:. |
Human   153 VPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCLHLDLSRL 217

  Fly   182 TKMGADNWS 190
            ...|...|:
Human   218 ASAGCSGWT 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7322	NP_573333.2	XR_like_SDR_c	1..242	CDD:187609	69/204 (34%)
DHRS4L2	NP_932349.2	Rossmann-fold NAD(P)(+)-binding proteins	24..>210	CDD:473865	66/186 (35%)