DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7322 and dhs-21

DIOPT Version :9

Sequence 1:	NP_001259693.1	Gene:	CG7322 / 32880	FlyBaseID:	FBgn0030968	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_506182.2	Gene:	dhs-21 / 179741	WormBaseID:	WBGene00000984	Length:	251	Species:	Caenorhabditis elegans

Alignment Length:	247	Identity:	110/247 - (44%)
Similarity:	142/247 - (57%)	Gaps:	13/247 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DLAGKVILVTGAGAGIGQALVKQLASAGATVIAVARKPEQLQQLVAFDP---VHIQPLQLDLSGW 65
            |...|.||||||..|||:.:...||.|||.|||.||....|..||....   ..|.|:..|:|
Worm     6 DFTDKRILVTGASQGIGKEICLSLAKAGAQVIAFARNEANLLSLVKETTSLRYTIIPIVGDVS-- 68

  Fly    66 QAVREGLAKVPL----LDGLVNNAGVAIIKPFEELTEQDFDTHFDVNIKAVFNVTQSLLPRLKD- 125
             |..|.|.|:.:    :.|||||||:|......::|:|..|..|.||::....:.|.:.....|
Worm    69 -ANEEVLFKLIVPHFPIHGLVNNAGIATNHAIGQITQQSIDRTFAVNVRGPILIAQLVARNFVDR 132

  Fly   126 --GASIVNVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSVNPTVVLTKMGADN 188
              ..||||:||.|:.|....||.|.|:|||||.:|:.||.|||.:.|||||||||||:|.||.||
Worm   133 QIKGSIVNISSQAAIRPLDNHTVYCASKAALDMVTRCLANELGSQNIRVNSVNPTVVMTDMGRDN 197

  Fly   189 WSDPAKSGPLLAHIPLNRFCEVQEVVDATGYLLSSKSSFVNGHHILLEGGYS 240
            ||||.|...:|..:|:.||.||.|||:|..:|||..:|...|..:.::||:|
Worm   198 WSDPDKKKKMLDRMPIKRFAEVDEVVNAVLFLLSDNASMTTGSTLPVDGGFS 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7322	NP_001259693.1	XR_like_SDR_c	1..242	CDD:187609	110/247 (45%)
dhs-21	NP_506182.2	PRK07060	1..249	CDD:180817	109/245 (44%)
dhs-21	NP_506182.2	XR_like_SDR_c	3..251	CDD:187609	110/247 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157723
Domainoid	1	1.000	163	1.000	Domainoid score	I2418
eggNOG	1	0.900	-	-		E1_KOG1207
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22964
Inparanoid	1	1.050	173	1.000	Inparanoid score	I2729
Isobase	1	0.950	-	1.057542	Normalized mean entropy	S1884
OMA	1	1.010	-	-		QHG52160
OrthoDB	1	1.010	-	-		D1051625at2759
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	1	1.000	-	-		oto17559
orthoMCL	1	0.900	-	-		OOG6_105139
Panther	1	1.100	-	-	LDO	PTHR44252
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2478
SonicParanoid	1	1.000	-	-		X1266
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750