Protein Alignment CG7322 and Hsd17b8

DIOPT Version :10

• Sequence 1: NP_573333.2
• Gene: CG7322 / 32880
• FlyBaseID: FBgn0030968
• Length: 242
• Species: Drosophila melanogaster
• Sequence 2: NP_038571.2
• Gene: Hsd17b8 / 14979
• MGIID: 95911
• Length: 259
• Species: Mus musculus
• Alignment Length: 260
• Identity: 82/260 - (31%)
• Similarity: 120/260 - (46%)
• Gaps: 36/260 - (13%)

  Fly     5 LAGKVILVTGAGAGIGQALVKQLASAGATVIAVARKPEQLQQLVAFDPVHI-------------- 55
            |...:.||||||:|||:|:..:||:.||.|.|.     .|....|.|.|.:
Mouse     7 LRSALALVTGAGSGIGRAISVRLAAEGAAVAAC-----DLDGAAAQDTVRLLGSPGSEDGAPRGK 66

  Fly    56 -QPLQLDLSGWQAVREGLAKV-------PLLDGLVNNAGVAIIKPFEELTEQDFDTHFDVNIKAV 112
             ...|.|:|...|.|..|.:|       |.:  :|:.||:...:....::|:|:|....||:|..
Mouse    67 HAAFQADVSQGPAARRLLEEVQACFSRPPSV--VVSCAGITRDEFLLHMSEEDWDRVIAVNLKGT 129

  Fly   113 FNVTQSLLPRLKDG---ASIVNVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNS 174
            |.|||:....|...   .||:|:|||.......|.|.|:::||.:..||::.|.|||...||.||
Mouse   130 FLVTQAAAQALVSSGGRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIRCNS 194

  Fly   175 VNPTVVLTKMGADNWSDPAK-SGPLLAHIPLNRFCEVQEVVDATGYLLSSKSSFVNGHHILLEGG 238
            |.|..:.|.|   ....|.| ...:.|.|||....:.::|.|...:|.|..|.::.|..:.:.||
Mouse   195 VLPGFIATPM---TQKMPEKVKDKVTAMIPLGHMGDPEDVADVVAFLASEDSGYITGASVEVSGG 256

  Fly   239  238
            Mouse   257  256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7322	NP_573333.2	XR_like_SDR_c	1..242	CDD:187609	82/260 (32%)
Hsd17b8	NP_038571.2	Rossmann-fold NAD(P)(+)-binding proteins	11..258	CDD:473865	81/256 (32%)