DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7322 and Cbr2

DIOPT Version :9

Sequence 1:	NP_001259693.1	Gene:	CG7322 / 32880	FlyBaseID:	FBgn0030968	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_031647.1	Gene:	Cbr2 / 12409	MGIID:	107200	Length:	244	Species:	Mus musculus

Alignment Length:	246	Identity:	109/246 - (44%)
Similarity:	154/246 - (62%)	Gaps:	6/246 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWTDLAGKVILVTGAGAGIGQALVKQLASAGATVIAVARKPEQLQQLVAFDPVHIQPLQLDLSGW 65
            |..:.:|...||||||.|||:..||.|.::||.|:||.|....|..|....| .|:|:.:||..|
Mouse     1 MKLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECP-GIEPVCVDLGDW 64

  Fly    66 QAVREGLAKVPLLDGLVNNAGVAIIKPFEELTEQDFDTHFDVNIKAVFNVTQ----SLLPRLKDG 126
            .|..:.|..:..:|.|||||.:.|::||.|:|::.||..|.||:::||.|:|    .::.|...|
Mouse    65 DATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMINRGVPG 129

  Fly   127 ASIVNVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSVNPTVVLTKMGADNWSD 191
             |||||||:.:..:|.....||:||.|:..|||::|:||||.||||||||||||||.||....:|
Mouse   130 -SIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVVLTDMGKKVSAD 193

  Fly   192 PAKSGPLLAHIPLNRFCEVQEVVDATGYLLSSKSSFVNGHHILLEGGYSVS 242
            |..:..|....||.:|.||::||::..:|||.:|:..:|..||::.||..|
Mouse   194 PEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDAGYLAS 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7322	NP_001259693.1	XR_like_SDR_c	1..242	CDD:187609	108/244 (44%)
Cbr2	NP_031647.1	XR_like_SDR_c	1..244	CDD:187609	108/244 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833837
Domainoid	1	1.000	207	1.000	Domainoid score	I2875
eggNOG	1	0.900	-	-		E1_KOG1207
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3586
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52160
OrthoDB	1	1.010	-	-		D1051625at2759
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	1	1.000	-	-		otm44291
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44252
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1266
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.870