DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shop and cyb5r2

DIOPT Version :9

Sequence 1:	NP_573331.1	Gene:	shop / 32878	FlyBaseID:	FBgn0030966	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_001038825.1	Gene:	cyb5r2 / 751641	ZFINID:	ZDB-GENE-060825-83	Length:	309	Species:	Danio rerio

Alignment Length:	199	Identity:	38/199 - (19%)
Similarity:	67/199 - (33%)	Gaps:	54/199 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 GSPWSQEPQRHALLKPASKRPFNAEPPIGLLAEQFYTP-------------NELFYVRNHLPVPV 249
            |.|.|.    |.|..|..:..:.:....|.|..:.|||             .:::|...|...|
Zfish    71 GLPSSS----HVLGLPIGQHIYLSAKVNGSLVVRAYTPVSSDQDQGYVDLVVKVYYKNTHPSYP- 130

  Fly   250 INPEDYELEIEGGAKDKTL-------TLD--GIKALPKHSVTAAIMCGGNRRSEMTKVKAVKGLS 305
                      :||...:.|       |:|  |...|..::.........:::|| .:|:..|.::
Zfish   131 ----------DGGKMSQYLDNMKIGDTIDFRGPNGLLVYNGKGKFAIRPDKKSE-AEVRKFKHVA 184

  Fly   306 WGAGAVG-----------NAKWSGARLCDILREQGVQPDETKHVIFEGADLDPTSHPYGASIPLA 359
            ..||..|           .|..|...:|.:     :..::|:..|....:||.....:.:.:.|.
Zfish   185 MIAGGTGITPMLQLVRSITADSSDETVCSL-----IFANQTEKDILLRNELDEVHRNHPSKLKLW 244

  Fly   360 KALD 363
            ..||
Zfish   245 YTLD 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shop	NP_573331.1	Cyt-b5	110..185	CDD:278597
		PLN00177	199..572	CDD:177772	37/198 (19%)
		eukary_SO_Moco	211..572	CDD:239029	33/186 (18%)
cyb5r2	NP_001038825.1	PTZ00319	9..309	CDD:173521	38/199 (19%)
cyb5r2	NP_001038825.1	cyt_b5_reduct_like	53..309	CDD:99780	38/199 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100179
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900