DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment shop and suox

DIOPT Version :9

Sequence 1:	NP_573331.1	Gene:	shop / 32878	FlyBaseID:	FBgn0030966	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_001120571.1	Gene:	suox / 100145725	XenbaseID:	XB-GENE-985202	Length:	568	Species:	Xenopus tropicalis

Alignment Length:	571	Identity:	273/571 - (47%)
Similarity:	353/571 - (61%)	Gaps:	34/571 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 RHHQHQRHHRRLLLTTSRGSNGERE-EQQHSQWS--SPGSRSEQLFYAAFWAGGLTLGYHWLTDK 76
            |.|:.|||...|.|   |....|.. :::||..:  ..|:..|...:.....|.| ||.
Frog    16 RSHRLQRHMLNLYL---RSCTVESVFDRKHSTEARLKAGNGKETTKWGIALTGAL-LGI------ 70

  Fly    77 KNHVLLEG--QKVASEEELEATARLWHVTNRRELPTYRAEEVEQHNSVEKRIWVTYGLGVYDVTD 139
             ..||:.|  :|..::.||..     |.......|.|..::|.:|.|:|.|:||||...|:|:|:
Frog    71 -GTVLIYGVPKKRVAQAELTT-----HTVATSTFPLYSKKDVSKHASMESRVWVTYEGEVFDITE 129

  Fly   140 FVENHPGGDKILMAAGSAIDPFWGIYQQHNTLEVLELLEGFRIGNLEGLVVTNVDDELGSPWSQE 204
            |:|.||||.:|::|||.|::|||.:|..|....|||:|:.:::|.|.........|| ..|:|||
Frog   130 FIELHPGGSRIMLAAGGALEPFWALYGVHKNEHVLEILKEYKVGELNSAEKDEPVDE-SDPYSQE 193

  Fly   205 PQRHALLKPASKRPFNAEPPIGLLAEQFYTPNELFYVRNHLPVPVINPEDYELEIE---GGAKDK 266
            |.||.:||..|.:|||||||..:|.|.|.||.:||:.|||||||.|||.||:||||   |..:||
Frog   194 PSRHPVLKVNSMKPFNAEPPPYMLTENFITPTDLFFKRNHLPVPRINPNDYKLEIERPNGKTQDK 258

  Fly   267 --TLTLDGIKA-LPKHSVTAAIMCGGNRRSEMTKVKAVKGLSWGAGAVGNAKWSGARLCDILREQ 328
              .|||..:|. .|||.:|..:.|.|||||||:.||.||||.|.:||:..|.|:||||.|:|.|.
Frog   259 PLNLTLSDLKTKFPKHEITVTLQCAGNRRSEMSAVKPVKGLDWNSGAISTAHWAGARLRDVLLEA 323

  Fly   329 GVQPD--ETKHVIFEGADLDPTSHPYGASIPLAKALDPRGDVILAYEMNDEPLSRDHGFPIRVIV 391
            |...|  :.:||.|||.|.|.|...|||||...:|:....:||||||||.:.|.:|||||:||||
Frog   324 GYTEDCSQAQHVHFEGLDRDMTGTNYGASISFQQAMARENEVILAYEMNGQELPQDHGFPLRVIV 388

  Fly   392 PGTVGARNVKWLTRIVVADKESDSHWQQNDYKGFSPSTDWDTVDFSKSDAIQAMPVTSAICTPQP 456
            ||.|||||||.|.:|:|:.:||.|||||||||||:|..|||.|||:.|.:||.:||.|||..|.|
Frog   389 PGVVGARNVKCLGKIIVSKEESGSHWQQNDYKGFNPCVDWDNVDFASSPSIQDLPVQSAITEPHP 453

  Fly   457 GARVKVDDDEGHITVRGYAWSGGGRKIVRVDLTNDEGVSWHVAELEQEEMPDGRHYGWSLWTARL 521
            |.:| ..:.||.:||:|||||||||:|||||::.|.|.:|.||||..|:...|:.:.|.||...:
Frog   454 GQKV-TPNFEGELTVKGYAWSGGGREIVRVDVSVDGGKTWKVAELTGEKQKTGQAWAWKLWQLNV 517

  Fly   522 PVSEAQRRAGDVEIWAKAVDSAYNVQPEKFEHIWNLRGVLANAYHKVKVKI 572
            |...   ...|..|..|||||:|||||:....||||||||.||:|:|.|.:
Frog   518 PFPS---NISDFTIICKAVDSSYNVQPDTVAPIWNLRGVLNNAWHRVHVTV 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shop	NP_573331.1	Cyt-b5	110..185	CDD:278597	34/74 (46%)
		PLN00177	199..572	CDD:177772	211/380 (56%)
		eukary_SO_Moco	211..572	CDD:239029	204/368 (55%)
suox	NP_001120571.1	Cyt-b5	100..175	CDD:278597	34/74 (46%)
		PLN00177	190..565	CDD:177772	210/378 (56%)
		eukary_SO_Moco	199..565	CDD:239029	204/369 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	200	1.000	Domainoid score	I2988
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H394
Inparanoid	1	1.050	501	1.000	Inparanoid score	I1327
OMA	1	1.010	-	-		QHG63137
OrthoDB	1	1.010	-	-		D288655at33208
OrthoFinder	1	1.000	-	-		FOG0004792
OrthoInspector	1	1.000	-	-		oto102752
Panther	1	1.100	-	-	LDO	PTHR19372
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4400
SonicParanoid	1	1.000	-	-		X3942
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110