DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment htk and RSC9

DIOPT Version :9

Sequence 1:	NP_573330.3	Gene:	htk / 32877	FlyBaseID:	FBgn0085451	Length:	2486	Species:	Drosophila melanogaster
Sequence 2:	NP_013579.1	Gene:	RSC9 / 854912	SGDID:	S000004596	Length:	581	Species:	Saccharomyces cerevisiae

Alignment Length:	441	Identity:	87/441 - (19%)
Similarity:	143/441 - (32%)	Gaps:	121/441 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 LRRTALCLKSGRHFNESETLDQLPLTHPEHFGNPVVGGRRGRRRGHLNEDSSEDDDESDAKEVVN 169
            |.::::|        :|:.:|.|.:               |.....:..:.::|.|  ..:.:|.
Yeast   141 LNKSSIC--------DSKAMDSLQM---------------GLNALLILRNLAQDTD--SVQILVK 180

  Fly   170 EKEEN------IGKVVCVETESKK----KDKEKWFPALV-------------VAPTA------QA 205
            ::|..      :.|..||.|...|    :....:|..|.             :||..      |.
Yeast   181 DREIKSFILFILKKFQCVATGDNKWQLYEGNATFFNELTHYTLDLMEAISSYIAPAMKDDHYFQT 245

  Fly   206 TVRI--RVKDEYLVRSFKDGRYYTVPKKEATEFTREVASKQ-----------------DVPAVQA 251
            .|.|  ..||.|:|.|........:.:.:|.|   |.|:..                 |...:.|
Yeast   246 LVSILNYTKDRYMVISILRSLSRLLVRSKANE---ESAADNLDHKTLSLIVSFLLLECDSELIIA 307

  Fly   252 ALEFLDSSVLPAHWDRDSLFGLTNISSDDEGEIDS----DSSDDEPH---EEKDRFVAQLYKYMD 309
            :|:||...:||.......||.....|...|..:.:    :.:..:.|   :.|.|.:.:|
Yeast   308 SLDFLYQYILPGSQRITELFKSKECSLILEATLPNLLSYNIATPDYHLLQKHKIRLIKRL----- 367

  Fly   310 DRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTSQNQWKLIAMRLGFTP---CTVSVMNLVK 371
              ..|..|.|..||.|     ||:.:.|   .|.......|    :|..|.|   ...:.::|.:
Yeast   368 --KPPAPKEPPNLSED-----LFQQLFK---LNEPLRSTAW----LRCCFEPVQEAEFTQISLWR 418

  Fly   372 QAYKKFLQPYGDFHRKLGCSMLMTSRNSNRSKGRSLVRANSVASPKPMETMKTETISKLAQP--N 434
            ....||.||..:..|||..::......||     :...|.::....|: |.|...:.|..||  .
Yeast   419 SYESKFGQPVRESGRKLLPAVEFIKNVSN-----AFNNAAAIVITDPV-TGKKRFVIKGIQPRFK 477

  Fly   435 QTNVVASTSSSAAAASVAASS--------TPARAVSTASQSAAEESGNTSE 477
            ...:......|....|...|.        ||||..|.......:|..:.|:
Yeast   478 ALGIADGERESQVPISALKSKFLNDSKEITPARQNSIPEVKFPQELSDVSK 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	RBB1NT	171..262	CDD:285392	27/138 (20%)
		ARID	299..381	CDD:279697	20/84 (24%)
		Tudor-knot	692..751	CDD:288553
RSC9	NP_013579.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13964
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.130