Protein Alignment htk and arid4b

DIOPT Version :9

• Sequence 1: NP_573330.3
• Gene: htk / 32877
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: XP_004914677.2
• Gene: arid4b / 733823
• XenbaseID: XB-GENE-1003570
• Length: 1267
• Species: Xenopus tropicalis
• Alignment Length: 1518
• Identity: 369/1518 - (24%)
• Similarity: 577/1518 - (38%)
• Gaps: 498/1518 - (32%)

  Fly     1 MQQMDDPPSLPVGTEVSAKYKGAFCEAKVSKVVRNIKVKVAYKQGLGSGIVSDDAIKAPTGQLRV 65
            |:.:|:||.|.|||:|||||:|||||||:....|.:|||..::|...:..|.||.:|.|   |:|
 Frog    20 MKSLDEPPYLSVGTDVSAKYRGAFCEAKIKSTKRLVKVKATFRQDSSTVEVQDDHVKGP---LKV 81

  Fly    66 GAVVEVRHPDRKELVEATITKIQDCSQYTVVFDDGDITTLRRTALCLKSGRHFNESETLDQLPLT 130
            |||||:|:|| ....||.|.|:.|.|.|||||||||..||||::||||..|||.:||||||||||
 Frog    82 GAVVEIRNPD-GTYQEAVINKLTDASWYTVVFDDGDEKTLRRSSLCLKGERHFAQSETLDQLPLT 145

  Fly   131 HPEHFGNPVVGGR--RGRRRGHLNED----SSEDDDESDAKEVVNEKEENIGKVVCVETESKKKD 189
            :|||||.||:|.:  ||||...::|:    ||.|:||::.|    ..:|.||.||||:...||
 Frog   146 NPEHFGTPVIGKKTSRGRRSNQIHEEESTSSSSDEDENECK----TSDELIGTVVCVDVGDKK-- 204

  Fly   190 KEKWFPALVVAPTAQATVRIRVKDEYLVRSFKDGRYYTVPKKEATEFTREVASKQDV--PAVQAA 252
            |..|.|||||:|.....:.:: ||..||||||||::.:||:||..:. .::::|.|:  .|:..|
 Frog   205 KATWVPALVVSPDCCDDITVK-KDFILVRSFKDGKFASVPRKEIRDI-NDISTKNDIFKQALDQA 267

  Fly   253 LEFLDSSVLPAHWDRDSLFGLTNISSDDEGEIDSDSSDDEPHE----------EKDRFVAQLYKY 307
            |||..:..:||:|..:.....::..::::.|.:.|:.||...|          |::.|:.||||:
 Frog   268 LEFCKTKTIPANWVTEVKEESSSSETEEDEEQNKDNDDDNTSEEEEEIEPFPGERENFLQQLYKF 332

  Fly   308 MDDRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTSQNQWKLIAMRLGFTPCTVSVMNL--- 369
            |:|||||:||.|.:..|:::|::|||.|.|.||:|.:.|...||.:...||     :.::|.
 Frog   333 MEDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGFNNIDSGAIWKQVYQDLG-----IPILNSAAG 392

  Fly   370 --VKQAYKKFLQPYGDFHRKLGCSMLMTSRNSNRSKGRSLVRANSVASPKPMETMKTETISKLAQ 432
              ||.||:|:|..:.::     |    ||.|.                     :...|...|:|
 Frog   393 YNVKCAYRKYLYGFEEY-----C----TSANI---------------------SFHMELPIKIA- 426

  Fly   433 PNQTNVVASTSSSAAAASVAASSTPARAVSTASQSAAEESGNTSESSVVVEPPKKQRKGSAASSQ 497
                                             |...:|..:.::.||..|           |..
 Frog   427 ---------------------------------QKVCKEGVHENKVSVKQE-----------SES 447

  Fly   498 QGKVKSLVEKYEEKSTAVQATSSGTVAGSGASASAAAMPTTSAAASTATNLSSATSGGSATIATT 562
            ||  :::.|:::.|...:
 Frog   448 QG--ETVKEEFDTKHETI----------------------------------------------- 463

  Fly   563 AMNKDAESDLPLAKIKAAAVAAASTRHSMEKETNISSGSSASASSKANSAEMQRS-------RDA 620
                  .:::.:.:||          ||..||   ..|....:.||....|...:       .:.
 Frog   464 ------NNEVNINEIK----------HSTVKE---FIGVHLCSESKVKEVEEHIAVNQETILEEI 509

  Fly   621 SPSVAAPPSAGASTSGAAATAQTASNKKEKHQRSKQADKEKDKDKEEKQASSGKRKKEKISVEKI 685
            :|.:                .:|....|||.:  .:..||::.|:.:...:..:...|....|..
 Frog   510 TPKI----------------EETIITDKEKTE--AEIKKEEELDENQHMETENEDSAEGEEFESY 556

  Fly   686 DTGDFVVGIGDKLKVNYHEKKSPSSHGSTYEAKVIEISVQRGVPMYLVHYTGWNNRYDEWVPRER 750
            .:       |.|::|.|...|:.    ..|||.|.:..|:.|..:|||||.|||.|||||:..::
 Frog   557 PS-------GMKVQVRYGRGKNQ----KLYEASVKDSDVEGGEVLYLVHYCGWNVRYDEWIKADK 610

  Fly   751 IA--------------------ENLTKGSKQ--------------------KTRTISTSSANSGS 775
            |.                    |:..|..:.                    :..:|.....|..|
 Frog   611 IVRPADKSVPKIKHRKKIKNKLEHRDKSERDECSPKHCRLFPRPLFQPRDLENESIQDDPENKHS 675

  Fly   776 GGGGGGGGGGGGGGGGGGGSLLVQ------GSQPPGVSDKQPGKDGCS----------------- 817
                            ..|..:|:      |.|....|.:....|..|
 Frog   676 ----------------LQGHTMVEITSILNGLQAAENSAEDSETDHSSLNMDKEEKAFHMNHISY 724

  Fly   818 ---------KMSP-SSGNSTGPGAPSLSGSLGGASSTPSLLSTV-------------------VK 853
                     |..| :.||.||     |...|.....:|.||.||                   :|
 Frog   725 DINQRLDENKSFPLTEGNCTG-----LDPILAVIPRSPDLLKTVEDSSDDTDYEVESARQSKYLK 784

  Fly   854 TPPTGGA-KRGRGRSDSMPPRSTTPSSVVAHSGRTKSPAASQPQLQQQMKKRPTRVVPGTTTPRR 917
            ...|... |||:.:...|              |:.:||..::...:            ...|..|
 Frog   785 NDITKSQNKRGKRKYTEM--------------GKARSPNGNEVYSK------------CNETTDR 823

  Fly   918 VSDASMASESDSDSDEPVR---------RPKRQSAKDKPQAGKAQPPGKG-RLASSAS------- 965
            :...||.|..|.:...|..         ..||:|.:.....|.::.|.|. :|.:::.
 Frog   824 LDAGSMTSSDDEEKSNPKHALSNKYNGFEDKRKSLRTGFYTGFSETPEKKIKLLNNSEERLRAKD 888

  Fly   966 -----STAPAAHPSDDSEEDEEEEEPSAARAASSKQQQQQASSLRGSRAGGNRAMSSGAASAKGR 1025
                 |:.....|....:|...:.:...|.:.|:: .|.::|||:.|.  .|..|||...|...:
 Frog   889 RKDVWSSIQGQWPKKTLKELFSDSDTEGATSPSTR-NQDESSSLQQSH--DNIRMSSSEVSKPEK 950

  Fly  1026 DYDL-------SEIRSELKGF-----------------QPKLLTNAASNEERKD-LAKKEPSDEP 1065
            |..|       :||..:...|                 .|..|:.....:.:.| |...||:.|.
 Frog   951 DNGLKPVDERAAEISDKKIDFPSSGSNSVLNTPPTTPESPSTLSECQKQQSKSDILDTLEPNQEE 1015

  Fly  1066 A-------------------LQDIKKEPKLE--------SSAKSSSTELSSETESYADE------ 1097
            .                   |||::.|.:..        ||:.|:..|..|:.:|:.::
 Frog  1016 VQSMKSETDSTIEVDSVTCELQDLQYEGRFSPTGFDASISSSSSNQQEPESKEKSHTNQAVDQTV 1080

  Fly  1098 ---DSQSSDYRKQLKGSGAGKKEPTASPSKLHH----EPVTKRE-----LAVKEEPLKIEPK--- 1147
               |:.|...::..|.|...||....:.|....    |.:||.:     :.:|.:|.|:..:
 Frog  1081 NVGDNSSKKLKRSHKSSVFQKKRKITNTSDSEDLSGGESLTKMQSERPNVGLKSQPTKVPLRVHS 1145

  Fly  1148 ----TEPKEEETKSKPFLSGADIKPTALIAPARFGNTSAAQAASSSGSSSTTAKYTSVIVEKPLT 1208
                .:.:|::|..|.:   ||..|               :....|...|...|.|
 Frog  1146 PGKYAKNREKDTFQKEY---ADRLP---------------KVYKWSFQMSDLEKMT--------- 1183

  Fly  1209 IGGKKSVEQ--HVPKKAELLKKQSGGAGGTAASSSAASQESKKFAEPVASLKVEMPAACSPSSSS 1271
                 |:|:  .:.:|.:.|:|.........||.....:..||.....|   |...::.||||||
 Frog  1184 -----SIERIAFLQEKLQELRKHYLSLKSEVASIDRRRKRCKKKERESA---VVSSSSSSPSSSS 1240

  Fly  1272 SSSSSFCSTGSAVSSSSATRSLP 1294
            .:::...:......|||:..::|
 Frog  1241 ITAAVMLTLAEPTLSSSSQNAMP 1263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	RBB1NT	171..262	CDD:285392	38/92 (41%)
		ARID	299..381	CDD:279697	36/86 (42%)
		Tudor-knot	692..751	CDD:288553	24/58 (41%)
arid4b	XP_004914677.2	Tudor_ARID4B_rpt1	20..80	CDD:410531	30/62 (48%)
		Tudor_ARID4B_rpt2	81..137	CDD:410533	35/56 (63%)
		RBB1NT	188..278	CDD:400474	38/93 (41%)
		ARID_ARID4B	321..412	CDD:350647	38/104 (37%)
		PTZ00341	<431..556	CDD:173534	29/221 (13%)
		CD_CSD	560..617	CDD:421697	24/60 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	181	1.000	Domainoid score	I3419
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	433	1.000	Inparanoid score	I1671
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003167
OrthoInspector	1	1.000	-	-		otm48658
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2560
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.050