Protein Alignment htk and arid6

DIOPT Version :10

• Sequence 1: NP_573330.3
• Gene: htk / 32877
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: NP_001073670.1
• Gene: arid6 / 572528
• ZFINID: ZDB-GENE-070112-1882
• Length: 603
• Species: Danio rerio
• Alignment Length: 740
• Identity: 154/740 - (20%)
• Similarity: 249/740 - (33%)
• Gaps: 258/740 - (34%)

  Fly   291 DEPHEEKDRFVAQLYKYMDDRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTSQNQWKLIAM 355
            ||..||  ||:..||.:|.|||||:.::|.:..:.:|::.:::.|::.|||.:||:|..||.:..
Zfish    16 DEMSEE--RFLKDLYLFMKDRGTPIERIPHLGFKQIDMFLMYKTVKELGGYQQVTTQQLWKKVYN 78

  Fly   356 RLGFTPCTVSVMNLVKQAYKKFLQP---------------------------YGDFHRKLGCSML 393
            .||..|.:.|.....::.|:|.|.|                           |.||.::.
Zfish    79 ILGGNPRSTSAATCTRRHYEKLLLPYECHQTGYRDDLVFRSPRPQKRFHPSSYHDFEQEY----- 138

  Fly   394 MTSRNSNRSKGRSLVRANSVASPKPMETMKTETISKLAQPN---------QTNVVASTSSSAAAA 449
              .||..|...|.|     ...|:...:|.||.....:.|:         .:|.:|...|:....
Zfish   139 --PRNDKRPDFRHL-----PVFPQTSPSMFTEQRPIFSMPSPFFPHGSTPMSNYIALRESTLPHL 196

  Fly   450 SVAAS----STPARAVSTASQSAAEESGNTSESSVVVEPPKKQRKGSAASSQQGKVKSLVEKYEE 510
            |:..|    .|||..:|..|..|              :..|:..|         .::.|..:|.
Zfish   197 SLNPSHDLPRTPASYMSVPSMDA--------------QICKRSIK---------TLRDLANEYR- 237

  Fly   511 KSTAVQATSSGTVAGSGASASAAAMPTTSAAASTATNLSSATSGGSATIATTAMNKDAESDLPLA 575
                                       ::|......|| |.|.....|::.|..:....|..|..
Zfish   238 ---------------------------STAGLEEPLNL-SRTENRLETLSDTPSSFSPCSKKPKF 274

  Fly   576 KIKAAAV---AAASTRHSMEK-----ETNISSGSSASASS--KANSAEMQRSRDAS--PSVAAPP 628
            ..||:::   .:.||....|:     ||:...||..|..|  |.:..::..|.:|:  |...:||
Zfish   275 LNKASSLYPQRSLSTEDGAEQEEPADETSTGEGSVRSGPSPPKPDVIDLTSSSNANPVPRRPSPP 339

  Fly   629 SAGASTSGAAATAQTASNKKEKH-----QRSKQADKEKDKDKEEKQASSGKRKKEKISVEKIDTG 688
            |.            ...|::..:     .:|::.|..||..|||   |||
Zfish   340 SV------------NLFNRRPHYSEAVTMKSRERDLHKDWVKEE---SSG--------------- 374

  Fly   689 DFVVGIGDKLKVNYHEKKSPSSHGSTYEAKVIEISVQRGVPMYLVHYTGWNNRYDEWVPRERIAE 753
                              :|:       .|::..|...|:|:     ...|:..:..:|.:.:.|
Zfish   375 ------------------APA-------PKLVHRSNPLGLPI-----PESNSNMEIQIPLKLLHE 409

  Fly   754 NLTKGSKQKTRTISTSSANSGSGGGGGGGGGGGGGGGGGGGSLLVQGS--QPPGVSDKQPGKD-- 814
            .:.:|          ..:|.|                     |...||  |.|..::.||...
Zfish   410 LIRRG----------MISNPG---------------------LTANGSAFQDPTKAEAQPEHKFH 443

  Fly   815 --GCSKMSPSSGNSTGPGAPSLSGSLGGASSTPSLLSTVVKTPPTGGAKRGRG-RSDSMPPRSTT 876
              ..|:.|.||..:..|...||..:....:...|..:.:.|....|    |.| .:||.|...:
Zfish   444 VRSRSESSESSSTAEEPANLSLKSAFRNPTDPISQDNAMKKLRLFG----GNGVPTDSKPQMFS- 503

  Fly   877 PSSVVAHSGRT----KSPAASQPQLQQQMKKRPTRVVPGTTTPRRVSDASMASESDSDSDE-PV- 935
             |..|.||.:.    .:|..|||:|.|              .|...:..||.....|.|:| |:
Zfish   504 -SYQVNHSLKVTLERDAPRPSQPKLVQ--------------VPVIKNQESMNHRLHSYSEESPLS 553

  Fly   936 ------RRPK-----RQSAKDKPQA 949
                  |:|:     ...||:.|.:
Zfish   554 LTMKLGRKPEVKATSNTEAKEIPSS 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	Tudor_ARID4_rpt1	10..60	CDD:410460
		Tudor_ARID4_rpt2	65..118	CDD:410461
		RBB1NT	170..263	CDD:462390
		ARID	296..381	CDD:460187	30/111 (27%)
		CBD_RBP1_like	698..758	CDD:350843	8/59 (14%)
arid6	NP_001073670.1	ARID_ARID5	19..105	CDD:350633	31/87 (36%)