Protein Alignment htk and LOC5667807

DIOPT Version :10

• Sequence 1: NP_573330.3
• Gene: htk / 32877
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: XP_061518199.1
• Gene: LOC5667807 / 5667807
• VectorBaseID: AGAMI1_005783
• Length: 1844
• Species: Anopheles gambiae
• Alignment Length: 2175
• Identity: 403/2175 - (18%)
• Similarity: 669/2175 - (30%)
• Gaps: 782/2175 - (35%)

  Fly   436 TNVVASTSSSAAAASVAASSTPARAVSTASQSAAEESGNTSE--------------------SSV 480
            ::|.:..:|||..:.....||...|::.|:.|:...|.:||.                    .||
Mosquito    37 SSVASQPASSAPGSGGPLHSTANAAITPAATSSTGNSSSTSNGHDRRRPSVDIPSEGIADSPGSV 101

  Fly   481 VVEPPKKQRK----GSAASSQQGKVKSLVEKYEEKSTAVQATSSGTVAGSGASASAAAMPTTSAA 541
            ...||...|.    |..|..:|.      |:.:::|:.....::.....:.|::|||.|   :..
Mosquito   102 STPPPATSRSPGKGGEPAGEEQD------ERMKDRSSNNGGHNTAQCNQTNANSSAAPM---NGG 157

  Fly   542 ASTATNLSSATSGGSATIATTAMNKDAESDLPLAKIKAAAVAAASTRHSMEKETNISSGSSASAS 606
            :||:   ||:.||.|.:.:|:..|.|:..:                    ...::.:.|||:..|
Mosquito   158 SSTS---SSSGSGNSGSNSTSNSNSDSNGN--------------------SGSSSANGGSSSGKS 199

  Fly   607 SKANSAEMQRSRDASPSVAAPPSAGASTSGAAATAQTASNKKE-----KHQRSKQADKEKD---- 662
            ...|..:.::::....|......||...||...::...||...     .:..|:.|..::|
Mosquito   200 QNGNQPKPKQTQRKCVSENGNSGAGTGASGVGGSSTAGSNGTSTRAGINNNLSRLASLDRDHHYR 264

  Fly   663 ------------------------------KDKEE-------------KQASSGKR---KKEKIS 681
                                          :|:.|             :...||:.   :.|.::
Mosquito   265 PLVLALGDCIPVRPWSDSPIACLAELRMVWRDRNEQCLLIALRLYFLPENTPSGRNCHGEDEVLA 329

  Fly   682 VEK------------IDT-GDFVVGI---------GDKLKVNYHEKKSPS---------SH-GST 714
            :..            ||| .::..|:         .|.|.:..|..|:.|         .| |..
Mosquito   330 ISDKVILRAEDLLNWIDTEQEWSWGLLTLYDEQSAKDCLGMTRHLSKNSSLDFGDVDKEKHSGEN 394

  Fly   715 YEAKVIEISVQR--------------------------------GVPMYLVHYTGWNNRYDEWVP 747
            ...||..:|..|                                .||...:.:......|.|...
Mosquito   395 IVTKVAVLSFSRYCRYRSMLKRLEGVQDAWLRSTLVANLSGFVAPVPNMRIMFCKETFDYPELET 459

  Fly   748 RERIAENLT-------KGSKQKTRTISTSSANSGSGGGGGGGGGGGGGGGGGGGSLLVQGSQPPG 805
            .|.:..:|.       :|.::|  |:|.||                            |.::..|
Mosquito   460 HELLCNHLAPKLKGRPRGKRKK--TLSDSS----------------------------QYTKKEG 494

  Fly   806 VSDKQPGKDGCSKMSPSSGNSTGPGAPSLSGSLGGASSTPSLLSTVVKTPPTG--GAKRGRGRSD 868
            .||:....:  |.:|..|.:...||                  ..|:...||.  ..:..||.|.
Mosquito   495 CSDESESNE--SDISDYSYSKVSPG------------------KKVIDLHPTPRYNPRPSRGSSQ 539

  Fly   869 SMPPRSTTPSSVVAHSGRTKSPAASQPQLQQQMKKRPTRVVPGTTTPRRVSDASMASESDSDSDE 933
            :   :....|.|::.|..|..|:|....|.|:.:.:.|            |.|...|...|...:
Mosquito   540 T---KQEPISVVISASAGTVKPSAGSNHLSQRNRSKST------------SKAPKPSSKKSSKSK 589

  Fly   934 PVRRPKRQSAKDKPQAGKAQPPGKGRLASSASSTAPAAHPSDDSEEDEEEEEPSAARAASSKQQQ 998
            |.|:|.|.|:.:.....:.   ||...:||::|:..||..:.:|||||||.:..
Mosquito   590 PGRKPGRGSSSNNNNNNRG---GKKSSSSSSNSSLAAAGGAGESEEDEEEPDED----------- 640

  Fly   999 QQASSLRGSRAGGNRAMSSGAASAKGRDYDLSEIRSELKGFQPKLLTNAASNEERKDLAKKEPSD 1063
                   |...||..:.:.||:..:.|:.|..|                  :||..|..:.|..:
Mosquito   641 -------GEEDGGGSSSTRGASKDRDREEDADE------------------DEEEMDYEEDEEEE 680

  Fly  1064 EPALQDIKKEPKLESSAKSSSTELSSETESYAD------EDSQSSD------------------- 1103
            :..|.      ::.....|:..|.....:.:.|      .|||::.
Mosquito   681 DDNLF------RVNDRMGSAEREFLQRLQEFLDPRALQYADSQAATLKNVSLYAVYVKVQKIGGY 739

  Fly  1104 --------YRKQLKGSGA-------GKKEPTASPSKLH-------HEPVTKRELAV-----KEEP 1141
                    :.:.|:|:||       .|.|....|.:.|       .|...||:.|:     .|..
Mosquito   740 SAVTDKEVWNQLLQGTGAENGVLSRRKYEKIVLPFEKHLRELAGDQESDVKRDTALLLLGDDELD 804

  Fly  1142 LKIEPKTEPKEEETKSKPFLSGADIKPTALIAPARFGNTSAAQAASSSGSSSTTAKYTSVIVEKP 1206
            .|:....:.|.|  |..|     |.||..|              |.|:||:.........:|||.
Mosquito   805 AKLRLLRDVKVE--KRDP-----DSKPHEL--------------AESNGSAGLDYTVKRELVEKE 848

  Fly  1207 LTI---GGKKSVEQHVPKKAELLKKQSGGAGGTAASSSA---------------------ASQES 1247
            .:.   |||.:|           |:.|.||||.:.:...                     ..|:|
Mosquito   849 DSTYGGGGKCAV-----------KEDSNGAGGGSPNGGVHLGMSPVSVPLTVIVRPNLDEKDQKS 902

  Fly  1248 K--KFAEPVASLKVEM----PAACSPSSSSSSSSSFCSTGSAVSSSSATRSLPDMSKLEISSGTV 1306
            .  :..:|..::.|..    |.:.:...:...:|:.....|..|....|..:...::::|...||
Mosquito   903 SQIQIKQPHTTITVHQTTIHPHSANHHHAGQPNSNHHQPISGQSPQHITNQIQITNQIQIQQITV 967

  Fly  1307 -------PGATPGAAALQPSNVAQVSSSGAAKESKYSSSGGAAAGSGISMRKLLSSDVYEFKDTE 1364
                   ||...||                       ..||..:|:| |..:......|.||..:
Mosquito   968 QSNDKNGPGGVGGA-----------------------GGGGVGSGAG-SPNESAGQFKYSFKQDK 1008

  Fly  1365 PFEFEKRISPMASVGGTVAAAATAAGAMAAAGAASVIT------------------TMVPTPGAS 1411
            ..: |..|.|.|:...: |:|..|:||.:.:..||.::                  ::.||.|.
Mosquito  1009 SGQ-ELNIEPAATTPKS-ASATIASGAGSPSEGASSLSLFPLNRQGTDPDLTIKEVSVCPTSGT- 1070

  Fly  1412 GSGVAASASTSAPVVVGSAARKQALKASAIQHI-LEHQSPAAG---RERGGY------------G 1460
               ::.::|...|....        |.|:::|: :::....||   .|.||:            |
Mosquito  1071 ---LSITSSACVPTTPS--------KTSSLRHVRMKNDRKGAGGIMMEAGGFMGASQKENIPLLG 1124

  Fly  1461 GMTSSISLLTAPKLKK----------------RGSPLKEAALCMEKAKTYKLDKDQ--VQQPVEQ 1507
            |...|.||.....|..                .|.|:...|..........||:|.  .|||:
Mosquito  1125 GGVGSASLFGGQSLTTITPIPANMMMAGAFLGHGGPVPVGAGGSISTGRSALDQDHSGKQQPM-- 1187

  Fly  1508 KTQQLIQPTLGPVES--YGAGSPEAMSNLSTPTTSSGHAQLSASSTYS---------------QL 1555
             |..:....:..|:|  ....||.|.:: |.....:|.|.....|...               ::
Mosquito  1188 -TAPVATEVIDLVDSDNENDSSPPAGAS-SANRKQAGQAMRPIPSLLPPMKKRKLDILREGGLEV 1250

  Fly  1556 TP--HHATPFDALRKSPS----FNLNITALNEELAQTVQ-------------------------- 1588
            ||  :.|:.|.:|.|||.    ..:||||   ||..|.|
Mosquito  1251 TPISNGASIFSSLGKSPGPPNPMRINITA---ELNTTPQRPEPPKRSDHAPRKCIPTPLEFQTHC 1312

  Fly  1589 ---ETTRALTD--ALQPPSTPVPPTVSASGSTPTAVTPVITAMPTAGTAGLSCPSTPPTGANPVL 1648
               .|.:...|  .|.||..|.|.......:.|..|..::.||.:|  |.||     ..|..|.:
Mosquito  1313 MYTRTGKIFGDPKELVPPRVPAPAPDLLDLTGPRPVGLMMGAMDSA--ANLS-----NKGQQPPM 1370

  Fly  1649 ASPKLSTPPQAINASKQPPASH--------IVGSPFIETRNVFELSTSNEGSGYSSGESKDNKFE 1705
              |.:.....|.:.::..|||.        :|..|           |::.|||
Mosquito  1371 --PVMDFSSNARHTNRTGPASRTAPSLQITLVPGP-----------TNSHGSG------------ 1410

  Fly  1706 KLENVKILLAGAVGPFDLDAGSYEQKTSSIADKVLKAISQKKEEVENNKGKPPVEPAAAAKTPGR 1770
                      |.:|......|.                           |.||:........|
Mosquito  1411 ----------GGIGGVAPGMGG---------------------------GLPPMMTPLNIPVP-- 1436

  Fly  1771 EDVVPSPTAKLDLCSSAIKLDTLKLLSEPLKIQTGPLLGELYRPGPATSSPETKSILESSLPAKN 1835
               |||..|.....::|....:...:...                |.:.:.|...:.:..:....
Mosquito  1437 ---VPSQQAAAAAAAAAAVTSSTSAMGHK----------------PKSKAYEIVPLRDGGVGGAA 1482

  Fly  1836 SELSETIQKLECAIQQRKTPVGGALSLASSTAGT---PPTAHTPNSTATAGAGFSDESMDSTDSE 1897
            :.:.|...|:...      |...:.|.:.||.||   ||...|.......|.|.|..::..|.:.
Mosquito  1483 APMKEPSPKVTIG------PSSASSSSSGSTNGTIIPPPPPPTGQLAGLMGPGTSPNNLLETLAN 1541

  Fly  1898 QRLVIEDVIAEEHTTTTTTGEQKS--PGSQQEEGQ-TNTATMATAVTAETEGTSSSTPTPPVPAP 1959
            .:.|..|::|.   ..:::|..||  ||..|..|. .:.:.:|.....:|:...|::......|
Mosquito  1542 LQKVNPDLMAR---ILSSSGISKSSIPGLTQLLGTLADQSPLAPPAAKKTQRRRSNSQAAAAAA- 1602

  Fly  1960 VKLELGAKAMPGIQAPIPLKPAEGSSFAGKLTGVVQPPPLAKLQQQEELGQAQGQSKSISSFGIP 2024
                  |.|.....:|||..|:.|..     .|.:.||              .|.|.||.|....
Mosquito  1603 ------AAAAAASSSPIPTAPSPGLP-----PGSIPPP--------------AGASSSIPSPNAT 1642

  Fly  2025 IVLPEI---PASVVVATPALMVASAATVMRHSPGSTPNSQAPVLISPKTFLTAPKVGEVGGLLLK 2086
            ..:|..   |.|:.:..|:::.:|.:...:|.|   |.:.:|      |....|...::
Mosquito  1643 TSMPPFPMPPGSLGLVPPSMLHSSNSPSPQHHP---PQADSP------TSANHPLSQQI------ 1692

  Fly  2087 AYTGVSGAVGAAPAGSVIASAGGGGTPTVISNFPQQQQQASVLQASSEMPANYVLDAEMAEPSNS 2151
                                       .::.....||||..:.|.:||......:.|:.::....
Mosquito  1693 ---------------------------KLLQQVQLQQQQKFLQQKASEEQQKLHMLAQFSQKQQQ 1730

  Fly  2152 SAPVVARPFVMHAVGKELFNVVAPAASSPLISDPHNESINLLCEETIPGSP----APNYGGTDQL 2212
            .....:.|    :.|..:..|....|.|||                 ||:|    .|:.....::
Mosquito  1731 HQQPQSSP----SQGSPVSPVSTVGAGSPL-----------------PGTPPLAMPPSPVSVPRI 1774

  Fly  2213 -----PTAVNSALAIVGITPLPPDTPPPVP 2237
                 |:|..:|.|:  ::.|||....|.|
Mosquito  1775 PVVPPPSAAAAAAAV--LSGLPPGAGAPFP 1802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	Tudor_ARID4_rpt1	10..60	CDD:410460
		Tudor_ARID4_rpt2	65..118	CDD:410461
		RBB1NT	170..263	CDD:462390
		ARID	296..381	CDD:460187
		CBD_RBP1_like	698..758	CDD:350843	16/108 (15%)
LOC5667807	XP_061518199.1	None