Protein Alignment htk and retn

DIOPT Version :10

• Sequence 1: NP_573330.3
• Gene: htk / 32877
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: XP_061499049.1
• Gene: retn / 5667193
• VectorBaseID: AGAMI1_010029
• Length: 979
• Species: Anopheles gambiae
• Alignment Length: 798
• Identity: 149/798 - (18%)
• Similarity: 263/798 - (32%)
• Gaps: 241/798 - (30%)

  Fly   290 DDEPHEEKDRFVAQLYKYMDDRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTSQNQWKLIA 354
            :|:|  ::..|:..|:.:|..||||:|::|.:....:|||.|:..|..|||...|.::..|:.|.
Mosquito   302 NDDP--KRKEFLDDLFLFMQKRGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKLWQEII 364

  Fly   355 MRLGFTPCTVSVMNLVKQAYKKFLQPYGDFHRKLGC-SMLMTSRNSNRSKGR----------SLV 408
            ..|.......|....::..|.|:|.||....:.|.. :.|..:.:.||.:||          |:.
Mosquito   365 KGLHLPSSITSAAFTLRTQYMKYLYPYECEKKNLSTPAELQAAIDGNRREGRRSSYGQFDSPSVQ 429

  Fly   409 RANSVASPKPMETMKTETIS-------------------------------------KLAQPNQT 436
            |     ||.|....:...:|                                     |:.||.:.
Mosquito   430 R-----SPIPQGISQMPPLSLVSHVNQQQHHHRLLPPVGQIPNMLPAEFEQRMLNYIKMFQPKEM 489

  Fly   437 NVVASTSSSAAAASVAAS------------STPARAVSTASQSAAEESGNTSES----------- 478
            ....|....:|..::..|            ::|..:::|:.::..:.:.:.|||
Mosquito   490 GRSQSPDKLSALNAIDISRVALWNMYNPSPNSPPNSLNTSPENNMQSALDLSESPDHAMAAIKRE 554

  Fly   479 ---SVVVEPPKKQRKGSAASSQQGKVKSLVEKYEEKSTAVQATSSGTVAGSGASASAAAMPTTSA 540
               .|....|:....|....:::.........:....|..:..||........|
Mosquito   555 RDHPVDFSDPRDYGNGLGPPAKRSHHHHHSHHHNRSLTPQKLNSSSQDEDDARS----------- 608

  Fly   541 AASTATNL-SSATSGGSATIATTAMNKDAE-------SDLPLAKIKAAAVAAASTRHSMEKETNI 597
             .||..|| .:.:.|..||:.....:::.|       .|:..|...|||.|||..:|.:
Mosquito   609 -DSTPVNLRENGSHGRRATLDDDGDDEEDEMEDETTDEDMLRASFAAAAAAAAVNQHPL------ 666

  Fly   598 SSGSSASASSKANSAEMQRSRDASPSVAAPPSAGASTSGAAATAQTASNKKEKHQRSKQADKEKD 662
                                                   |.:.|.....::::.|:.:|..:|::
Mosquito   667 ---------------------------------------ALSLADHHLQQQQQQQQQQQQQRERE 692

  Fly   663 KDKEEKQASSGKRKKEKISVEKIDTGDFVVGIGDKLKVNYHEKKSPSSHGSTYEAKVIEISVQRG 727
            :.:::..|...::::::.....:.|.|..:...::|:.:..:|....|.....:.:  :...|:.
Mosquito   693 RIQQQVAAQQQQQQQQREQQHSLATLDLSILDRERLRCDSADKLKRQSQQQQQQQQ--QQQQQQL 755

  Fly   728 VPMYLVHYTGWNNRYDEWVPRE-RIAEN-----LTKGSKQKTRTISTSSANSGSGGGGGGGGGGG 786
            :..:.:|.....::....|.|| |..||     ||..|.:    :...|.|..|..|||||.|..
Mosquito   756 LDQHHLHQRQLQHQQQARVARELRKHENGDRLSLTPDSSE----LLHHSKNHLSTSGGGGGAGSD 816

  Fly   787 ------------------GGGGGGGGSLLV----QGSQPPGVSDKQPGKDGCSKMSPSSGNSTGP 829
                              |....|...|:|    .|.|..||....|         .||.|.:.|
Mosquito   817 PFSSPLGITGMQFKLISRGDASKGDQKLVVTMEFNGVQYEGVLFANP---------LSSANLSAP 872

  Fly   830 GA---PSLSGSLGGASSTPSLLSTVVKTPPTGGAKRGRGRSDSMPPRSTTPSSVVAHSGRTKSPA 891
            .|   ||.|.|...||...|::|.|                         .||..||   ..||
Mosquito   873 PASTPPSSSVSATSASPIGSMVSPV-------------------------KSSAAAH---IASP- 908

  Fly   892 ASQPQLQQQMKKRPTRVVPGTTTPRRVSDASMASESDSDSDEPVRRPKRQSAKDKPQAGKAQPPG 956
                 |.::.......:..........:.|::.|.:.|::         ...:.:|..|...||
Mosquito   909 -----LDERDSSASANIDVAAMGSALAATATVTSNASSNA---------TCIQQQPLDGAVTPP- 958

  Fly   957 KGRLASSASSTAPAAHPS 974
                 ::.|.|||:...|
Mosquito   959 -----AALSITAPSVGAS 971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	Tudor_ARID4_rpt1	10..60	CDD:410460
		Tudor_ARID4_rpt2	65..118	CDD:410461
		RBB1NT	170..263	CDD:462390
		ARID	296..381	CDD:460187	25/84 (30%)
		CBD_RBP1_like	698..758	CDD:350843	13/65 (20%)
retn	XP_061499049.1	None