Protein Alignment htk and retn

DIOPT Version :10

• Sequence 1: NP_573330.3
• Gene: htk / 32877
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: NP_788434.1
• Gene: retn / 45976
• FlyBaseID: FBgn0004795
• Length: 911
• Species: Drosophila melanogaster
• Alignment Length: 887
• Identity: 169/887 - (19%)
• Similarity: 269/887 - (30%)
• Gaps: 334/887 - (37%)

  Fly   241 ASKQDVPAVQAALEFLDSSVLPAHWDRDSLFGLTNISSDDEGEIDSDSSDDEPHEEKDRFVAQLY 305
            ||....|:.:.|..|..:|.             :|.|:..|....|..::....||:.:.|.|||
  Fly   237 ASPTAAPSGKEARHFAANSA-------------SNSSTSSEASNSSQQNNGWSFEEQFKQVRQLY 288

  Fly   306 KYMDD----------------RGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTSQNQWKLIA 354
            :..||                ||||:|::|.:....:|||.|:..|..|||...|.::..|:.|.
  Fly   289 EINDDPKRKEFLDDLFSFMQKRGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKLWQEII 353

  Fly   355 MRLGFTPCTVSVMNLVKQAYKKFLQPYGDFHRKLGCSMLMTSRNSNRSKGRSLVRANSVASPKPM 419
            ..|.......|....::..|.|:|.||....:.|
  Fly   354 KGLHLPSSITSAAFTLRTQYMKYLYPYECEKKNL------------------------------- 387

  Fly   420 ETMKTETISKLAQPNQTNVVASTSSSAAAASVAASSTPARAVSTASQSAAEESGNTSESSVVVEP 484
                                               ||||..     |:|.:  ||
  Fly   388 -----------------------------------STPAEL-----QAAID--GN---------- 400

  Fly   485 PKKQRKGSAASSQQGKVKSLVEKYEEKSTAVQAT--SSGTVAGSGASASAAAMPTTSAAASTATN 547
               :|:|..:|..|         ||.....:..|  |..::.|.....|..|:.|.:|.|:
  Fly   401 ---RREGRRSSYGQ---------YEAMHNQMPMTPISRPSLPGGMQQMSPLALVTHAAVAN---- 449

  Fly   548 LSSATSGGSATIATTAMNKDAESDLPLAKIKAAAVAAASTRHSMEKETNISSGSSA--------S 604
                             |:.|:          ||.|||:..|.:       .|:.|        .
  Fly   450 -----------------NQQAQ----------AAAAAAAAHHRL-------MGAPAFGQMPNLVK 480

  Fly   605 ASSKANSAEMQRSRDASPSVAAPPSAGASTSGAAATAQTASNKKEKHQRSKQADKEKD---KDKE 666
            ...::...|..:...|......||..|.:.......:|....::..||:.:|...::.   :.:.
  Fly   481 QEIESRMMEYLQLIQAKKEQGMPPVLGGNHPHQQQHSQQQQQQQHHHQQQQQQQSQQQHHLQQQR 545

  Fly   667 EKQASSGKRKKEKISVEKIDTGDFVVGIGDKLKVNYHEKKSP--SSHGSTYEAKVIEISVQRGVP 729
            ::..|....|.|.:|.:.            .|...||...||  |:|.|..:.:.:.:|   ..|
  Fly   546 QRSQSPDLSKHEALSAQV------------ALWHMYHNNNSPPGSAHTSPQQREALNLS---DSP 595

  Fly   730 MYLVHYTGWNNR-------------YDEWVPRERIAENL-------------------------- 755
            ..|.:......|             .|:..|.:|:...|
  Fly   596 PNLTNIKREREREPTPEPVDQDDKFVDQPPPAKRVGSGLLPPGFPANFYLNPHNMAAVAAAAGFH 660

  Fly   756 --TKGSKQKTRTISTSSANSGSGGGGGGGGGGGGGGGGGGGSLLVQGSQPPGVS----------D 808
              :.|.:|          ::.|.|........|.....|..|.:...|:|..::          |
  Fly   661 HPSMGHQQ----------DAASEGEPEDDYAHGEHNTTGNSSSMHDDSEPQQMNGHHHHQTHHLD 715

  Fly   809 KQPGKDGCSKMSPSSGNSTGPGAPSLSGSLGGASSTPSLLSTVVKTPPTGGAKRGRGRSDSMPPR 873
            |  ..|...:.||::..:||       ||:|...|:|      |.|...||||...|..| :|..
  Fly   716 K--SDDSAIENSPTTSTTTG-------GSVGHRHSSP------VSTKKKGGAKPQSGGKD-VPTE 764

  Fly   874 STTPSSVVAHSGRTKSPAASQPQL---QQQMKKRPTRVVPGTTTPRRVSDASMASESDSDSDEP- 934
            ....||    ||:. :|..:...|   |.|:.:..|                      .|:.||
  Fly   765 DKDASS----SGKL-NPLETLSLLSGMQFQVARNGT----------------------GDNGEPQ 802

  Fly   935 -----------------VRRPKRQSAKDKPQAGKAQPPGKGRLASSASSTAPAAHPSDDSEEDEE 982
                             ...|..||              :.|.:|...:.||..   ::.:::||
  Fly   803 LIVNLELNGVKYSGVLVANVPLSQS--------------ETRTSSPCHAEAPTV---EEEKDEEE 850

  Fly   983 EEEPSAARAASSKQQQQQASSLRGSRAGGNRAMSSGAASAKG 1024
            ||||.||...|.:...:|.:........|:..:.:|.|||.|
  Fly   851 EEEPKAAEEESHRSPVKQENEDVDQDMEGSEVLLNGGASAVG 892

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	Tudor_ARID4_rpt1	10..60	CDD:410460
		Tudor_ARID4_rpt2	65..118	CDD:410461
		RBB1NT	170..263	CDD:462390	6/21 (29%)
		ARID	296..381	CDD:460187	29/100 (29%)
		CBD_RBP1_like	698..758	CDD:350843	16/102 (16%)
retn	NP_788434.1	ARID_Dri-like	277..401	CDD:350645	41/209 (20%)