Protein Alignment htk and arid4a

DIOPT Version :9

• Sequence 1: NP_573330.3
• Gene: htk / 32877
• FlyBaseID: FBgn0085451
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: XP_005158686.1
• Gene: arid4a / 327404
• ZFINID: ZDB-GENE-050809-105
• Length: 1332
• Species: Danio rerio
• Alignment Length: 1495
• Identity: 397/1495 - (26%)
• Similarity: 581/1495 - (38%)
• Gaps: 387/1495 - (25%)

  Fly     1 MQQMDDPPSLPVGTEVSAKYKGAFCEAKVSKVVRNIKVKVAYKQGLGSGIVSDDAIKAPTGQLRV 65
            |:..|:|..|.|||:|||||:|||||||:..|.|.:||||..|....|.:|.||.:|.|   |||
Zfish     1 MKVADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRMVKVKVVLKGDSTSQVVQDDQVKGP---LRV 62

  Fly    66 GAVVEVRHPDRKELVEATITKIQDCSQYTVVFDDGDITTLRRTALCLKSGRHFNESETLDQLPLT 130
            |:.|||:.|: ..|.||.|:|:.|.|.|||||||||..|||||:||||..|||.|||||||||||
Zfish    63 GSTVEVKSPE-GGLSEAVISKLTDASWYTVVFDDGDEKTLRRTSLCLKGERHFAESETLDQLPLT 126

  Fly   131 HPEHFGNPVVGGR--RGRRRGHL-----NEDSSEDDDESDAKEVVNEKEENIGKVVCVETESKKK 188
            :|||||.||:|.:  ||||....     .|.||.:||:.|.:.:   .::.:|||.||::|
Zfish   127 NPEHFGTPVIGKKTNRGRRSSQAVAEDEKESSSSEDDDDDKRRL---NDDLLGKVACVQSE---- 184

  Fly   189 DKEKWFPALVVAPTAQATVRIRVKDEYLVRSFKDGRYYTVPKKEATEFTREVASKQDV---PAVQ 250
            ..:.|...||::|:....:.:: ||:.|||||.|.:::||.:|:..|...:..||.:.   ...:
Zfish   185 PDDSWLCVLVISPSCNDDLTVK-KDQCLVRSFADSKFHTVARKDVKEVNIDTLSKPEYSLRKGCE 248

  Fly   251 AALEFLDSSVLPAHWDRDSLFGLTNISSDDEGEIDSDSS----------------DDEPH-EEKD 298
            ||..||.:..:|..|..| |..:...||.||.:.|.|..                ||||. ||:|
Zfish   249 AAKLFLQNRQIPDRWKVD-LSEILESSSSDEDDEDEDGEGKEGEEEEKEPEPEEPDDEPDPEERD 312

  Fly   299 RFVAQLYKYMDDRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTSQNQWKLIAMRLGFTPCT 363
            .|:.||||:|:|||||:||.|.:..:|::|::|||.|...||.:.:.|.:.||.|.|.||.....
Zfish   313 HFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVHIHGGCDNIESGSIWKQIYMDLGIPVLN 377

  Fly   364 VSVMNLVKQAYKKFLQPYGDFHRKLGCSMLMTSRNSNRSKGRSLVRANSVASPKPMETMKTETIS 428
            .:....||.||:|:|..:.::.|...........|                .|:|.
Zfish   378 SAASYNVKTAYRKYLYGFEEYCRSAQIQFRTVHHN----------------EPRPD--------- 417

  Fly   429 KLAQPNQTNVVASTSSSAAAASVAASSTPARAVSTASQSAAEESGNTSE--SSVVVEPPKKQRKG 491
              .||...::                           :|..:||.|..|  ..|..||...:.|.
Zfish   418 --VQPEVQSI---------------------------KSVTKESENNDEMMQQVTAEPGTSEDKP 453

  Fly   492 SAASSQQGKVKSLVEKYEEKSTAVQATSSGTVAGSGASASAAAMPTTSAAASTATNLSSATSGGS 556
            :|.:.:                                         |.|.|........:..|.
Zfish   454 AADADE-----------------------------------------SDAESEKGRKDVCSPRGR 477

  Fly   557 ATIATTAMNKDAESDLPLAKIKAAAVAAASTRHSMEKETNISSGSSASASSKANSAEMQRSRDAS 621
            ....||.:..:.|   ||.:.|        .:...:||...|.|.        ||.|..:.:...
Zfish   478 RRCLTTPVKVEME---PLKQEK--------IKEEKKKEDTQSVGE--------NSGEEPKEKSDG 523

  Fly   622 PSVAAPPSAGASTSGAAATAQTASNKKEKHQRSKQADKEKDKDKEEKQASSGKRKKEKISVEKID 686
            .......|.....|...:......|..|:.....:.|:|:::|.::::....:|.:.:...|: :
Zfish   524 EIPGKRRSRRHEESDKDSEEDDDDNDDEEQDDDDEDDEEEEEDDDDEEEDYFERSRLRERDER-E 587

  Fly   687 TGDFVVG--------IGDKLKVNYHEKKSPSSHGSTYEAKVIEISVQRGVPMYLVHYTGWNNRYD 743
            .||   |        .|.|::|.|.:.|:.    ..|||.:.......|..:|||||.|||.|||
Zfish   588 EGD---GCEDSEHSLAGTKVRVKYGKGKTQ----KIYEANIKNTETDDGEVLYLVHYYGWNVRYD 645

  Fly   744 EWVPRERIAENLTKG---SKQKTRTISTSSANSGSGGGGGGGGGGGGGGGGGGGSLLVQ------ 799
            |||..:||...:.||   .|||.:..:........              ......::|:
Zfish   646 EWVKADRIIWPVDKGGTKKKQKKKVKNKEDEEKEK--------------EEDKTKVVVRRGRPPL 696

  Fly   800 GSQPPGVSDKQPGKDGCSKMSPSSGNSTGPGAPSLSGSLGGASSTPSLLSTVVKTPPTGG---AK 861
            .|.|||.|.|.|..:|.|    ||.||    .|:.:.:|.....||..     :|..|.|   :.
Zfish   697 KSTPPGTSRKTPSSEGRS----SSKNS----RPTDASALPNGDGTPRR-----RTRRTSGMYDSD 748

  Fly   862 RG---RGRSDSMPPRSTTPSSVVAHSGRTKSPAASQPQLQQQMKKRPTRVVPGTTTPRRVSDASM 923
            ||   .|.|........:|......:.||..|..::.:....:.:..|...|..|.|...|
Zfish   749 RGSNDSGNSSDDSEGEKSPEKKQEWTERTDPPPIAKQEAADDLPEESTTQEPAQTEPELPS---- 809

  Fly   924 ASESDSDSDEPVRRPKRQSAKDKPQAGKAQPP------------GKGRLASSASSTAPAAHPSDD 976
                     .|...|....::.||:...:.||            .|.||....|.| |...|:..
Zfish   810 ---------SPQEMPNFNESESKPEEDSSMPPTESDVGSPKMTAKKPRLKEPGSET-PTQTPAAA 864

  Fly   977 SEEDEEEEEPSAARAASSKQQQQQASSLRGSRAGGNRAMSSGAASAKGRDYDLSEIRSELKGFQP 1041
            :...|.||..:..|.....|:...:|.:...:          .....|.|.|     |..:...|
Zfish   865 NHHAETEEPSTPPRPVKKSQETPHSSPVERIK----------LVETAGSDTD-----SATEDIDP 914

  Fly  1042 KLLTNAASNEERKDLAKKEPSDEPALQDIKKEPKLESSAKSSSTELSSETESYADEDSQSSDYRK 1106
            ...|:||   :||...::.|..:..| |.|:|||..|..|:|..|...|:|.           |.
Zfish   915 PERTSAA---KRKINEQRTPEKKIRL-DRKEEPKTPSPVKTSPLEKKPESEK-----------RT 964

  Fly  1107 QLKGSGAGKKEPT-ASPSK---LHHE-PVTKRELAVK--------EEPLKI-------------- 1144
            ::.........|| :||||   :..| |...||:.:|        |:|..:
Zfish   965 EIVQKPEEPPNPTLSSPSKEVEIKSEMPSLTREVHLKLEAPCPDLEDPTTVANEEMMPQIGPEAL 1029

  Fly  1145 ----------EPKTEP--------KEEETKSKPFLSGADIKPTALIAPARFGNTSAA----QAAS 1187
                      |.|.:|        |||:...:|..|...:.....:.|.|..:.|:|    ::.|
Zfish  1030 VCHEVDLDDPEEKDKPSSEELPIMKEEKVLPQPLESPDHLHVLPAVGPPRLFSPSSAPSPDESHS 1094

  Fly  1188 SSGSSSTTAKYTSVIVEKPLTIGGKKSVEQHVPKKAELLKKQSGGAGGTAASSSAASQE------ 1246
            :...|..|.:..|| .|....:|..:|.             .|..|..::::||.:.|:
Zfish  1095 TKSESDATIEVDSV-AESQEGLGENEST-------------HSFDASASSSNSSISLQDRDGKDR 1145

  Fly  1247 -SKKFAEPVASLKVEMPAACSPSSSSSS-------SSSFCST---GSAVSSSSATRSLPDMSKLE 1300
             .|:..:            |:..|||..       ||..|.|   |:..||.|..:|:.|
Zfish  1146 GQKRLLD------------CTTVSSSKKQKRSQKRSSVGCKTEKNGAGHSSDSEDQSVMD----- 1193

  Fly  1301 ISSGTVPGATPGAAALQPSNVAQVSSSGAAKESKYSSSGGAAAGSGISMRKLLSSDVYEFKDTEP 1365
                       |:..|.|     |..|...|..|.|.|.|..:.|    .|.:..|.::.|.:.|
Zfish  1194 -----------GSNKLTP-----VKHSILPKNQKLSRSPGLGSPS----NKYIEKDKHKEKQSVP 1238

  Fly  1366  1365
            Zfish  1239  1238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htk	NP_573330.3	RBB1NT	171..262	CDD:285392	28/93 (30%)
		ARID	299..381	CDD:279697	35/81 (43%)
		Tudor-knot	692..751	CDD:288553	24/66 (36%)
arid4a	XP_005158686.1	TUDOR	58..113	CDD:295375	34/58 (59%)
		RBB1NT	171..260	CDD:285392	28/93 (30%)
		ARID	311..396	CDD:198082	36/84 (43%)
		Tudor-knot	601..654	CDD:288553	24/56 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594220
Domainoid	1	1.000	176	1.000	Domainoid score	I3569
eggNOG	1	0.900	-	-		E1_KOG2744
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	389	1.000	Inparanoid score	I1952
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003167
OrthoInspector	1	1.000	-	-		otm26200
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13964
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	1	1.000	-	-		X2560
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.970