Protein Alignment Pvf1 and VEGFC

DIOPT Version :10

• Sequence 1: NP_523407.1
• Gene: Pvf1 / 32876
• FlyBaseID: FBgn0030964
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_005420.1
• Gene: VEGFC / 7424
• HGNCID: 12682
• Length: 419
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 46/230 - (20%)
• Similarity: 75/230 - (32%)
• Gaps: 61/230 - (26%)

  Fly   124 NFKRSIMKSTVRNATPASCSPQPTIVELKPPAEDEANYYYMPACTRISRCNGCCGSTLISCQPTE 188
            ::...|:||.........|.|:...:::........|.::.|.|..:.||.|||.|..:.|..|.
Human   113 HYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSVYRCGGCCNSEGLQCMNTS 177

  Fly   189 VEQVQLRVRKVDRAATSGRRPFTIITVEQHTQCRC-----------------------DCRTKAE 230
            ...:...:.::....:.|.:|.| |:...||.|||                       .|:...:
Human   178 TSYLSKTLFEITVPLSQGPKPVT-ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANK 241

  Fly   231 DCNVYQSYRKDLCRCECH-----NTDARDKCLEQ-----AENKYWVDDNCTCVCR---------- 275
            .|.....:...:|||...     ::||.|...:.     ..||...::.|.||||
Human   242 TCPTNYMWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLRPASCGP 306

  Fly   276 -----------------YNQSCTTGTVFDETQCKC 293
                             :...|.....|||..|:|
Human   307 HKELDRNSCQCVCKNKLFPSQCGANREFDENTCQC 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pvf1	NP_523407.1	PDGF	140..226	CDD:238079	22/108 (20%)
VEGFC	NP_005420.1	PDGF	129..213	CDD:197537	22/84 (26%)
		4 X 16 AA repeats of C-X(10)-C-X-C-X(1,3)-C	280..362		13/62 (21%)