Protein Alignment Pvf1 and VEGFA

DIOPT Version :10

• Sequence 1: NP_523407.1
• Gene: Pvf1 / 32876
• FlyBaseID: FBgn0030964
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_001020537.2
• Gene: VEGFA / 7422
• HGNCID: 12680
• Length: 412
• Species: Homo sapiens
• Alignment Length: 189
• Identity: 42/189 - (22%)
• Similarity: 63/189 - (33%)
• Gaps: 69/189 - (36%)

  Fly   142 CSPQPTIVELKPPAEDEANYYYMPACTRISRCNGCCGSTLISCQPTEVEQVQLRVRKV--DRAAT 204
            |.|..|:|::.....||..|.:.|:|..:.||.|||....:.|.|||...:.:::.::  .:...
Human   232 CHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQH 296

  Fly   205 SGRRPFTIITVEQHTQCRCDCRTKAE--------------------------------------- 230
            .|...|.     ||.  :|:||.|.:
Human   297 IGEMSFL-----QHN--KCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGARCCLM 354

  Fly   231 --------DCNVYQSYRKDL-------CRCECHNTDARDKCLEQAENKYWVDDNCTCVC 274
                    .|......||.|       |:|.|.|||:|.|..:...|:.      ||.|
Human   355 PWSLPGPHPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNER------TCRC 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pvf1	NP_523407.1	PDGF	140..226	CDD:238079	23/85 (27%)
VEGFA	NP_001020537.2	PDGF	230..312	CDD:197537	24/86 (28%)
		VEGF_C	364..412	CDD:405273	16/50 (32%)